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A proposed eye irritation testing strategy to reduce and replace in vivo studies using Bottom-Up and Top-Down approaches.
Scott L, Eskes C, Hoffmann S, Adriaens E, Alepée N, Bufo M, Clothier R, Facchini D, Faller C, Guest R, Harbell J, Hartung T, Kamp H, Varlet BL, Meloni M, McNamee P, Osborne R, Pape W, Pfannenbecker U, Prinsen M, Seaman C, Spielmann H, Stokes W, Trouba K, Berghe CV, Goethem FV, Vassallo M, Vinardell P, Zuang V. Scott L, et al. Among authors: harbell j. Toxicol In Vitro. 2010 Feb;24(1):1-9. doi: 10.1016/j.tiv.2009.05.019. Epub 2009 May 31. Toxicol In Vitro. 2010. PMID: 19490935 Review.
Cosmetics Europe multi-laboratory pre-validation of the EpiOcular™ reconstituted human tissue test method for the prediction of eye irritation.
Pfannenbecker U, Bessou-Touya S, Faller C, Harbell J, Jacob T, Raabe H, Tailhardat M, Alépée N, De Smedt A, De Wever B, Jones P, Kaluzhny Y, Le Varlet B, McNamee P, Marrec-Fairley M, Van Goethem F. Pfannenbecker U, et al. Among authors: harbell j. Toxicol In Vitro. 2013 Mar;27(2):619-26. doi: 10.1016/j.tiv.2012.11.007. Epub 2012 Nov 16. Toxicol In Vitro. 2013. PMID: 23159500
Eye irritation.
Eskes C, Bessou S, Bruner L, Curren R, Harbell J, Jones P, Kreiling R, Liebsch M, McNamee P, Pape W, Prinsen MK, Seidle T, Vanparys P, Worth A, Zuang V. Eskes C, et al. Among authors: harbell j. Altern Lab Anim. 2005 Jul;33 Suppl 1:47-81. doi: 10.1177/026119290503301s09. Altern Lab Anim. 2005. PMID: 16194141 No abstract available.
A summary report of the COLIPA international validation study on alternatives to the draize rabbit eye irritation test.
Brantom PG, Bruner LH, Chamberlain M, De Silva O, Dupuis J, Earl LK, Lovell DP, Pape WJ, Uttley M, Bagley DM, Baker FW, Bracher M, Courtellemont P, Declercq L, Freeman S, Steiling W, Walker AP, Carr GJ, Dami N, Thomas G, Harbell J, Jones PA, Pfannenbecker U, Southee JA, Tcheng M, Argembeaux H, Castelli D, Clothier R, Esdaile DJ, Itigaki H, Jung K, Kasai Y, Kojima H, Kristen U, Larnicol M, Lewis RW, Marenus K, Moreno O, Peterson A, Rasmussen ES, Robles C, Stern M. Brantom PG, et al. Among authors: harbell j. Toxicol In Vitro. 1997 Feb-Apr;11(1-2):141-79. doi: 10.1016/s0887-2333(96)00069-0. Toxicol In Vitro. 1997. PMID: 20654303
The principles of good laboratory practice: application to in vitro toxicology studies.
Cooper-Hannan R, Harbell JW, Coecke S, Balls M, Bowe G, Cervinka M, Clothier R, Hermann F, Klahm LK, de Lange J, Liebsch M, Vanparys P. Cooper-Hannan R, et al. Among authors: harbell jw. Altern Lab Anim. 1999 Jul-Aug;27(4):539-77. doi: 10.1177/026119299902700410. Altern Lab Anim. 1999. PMID: 25487864 No abstract available.
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