Bazzo R - Search Results

1

Cyclic phosphoramidates as prodrugs of 2'-C-methylcytidine.

Meppen M, Pacini B, Bazzo R, Koch U, Leone JF, Koeplinger KA, Rowley M, Altamura S, Di Marco A, Fiore F, Giuliano C, Gonzalez-Paz O, Laufer R, Pucci V, Narjes F, Gardelli C. Meppen M, et al. Among authors: bazzo r. Eur J Med Chem. 2009 Sep;44(9):3765-70. doi: 10.1016/j.ejmech.2009.04.043. Epub 2009 May 8. Eur J Med Chem. 2009. PMID: 19493593

2

Prime site binding inhibitors of a serine protease: NS3/4A of hepatitis C virus.

Ingallinella P, Fattori D, Altamura S, Steinkühler C, Koch U, Cicero D, Bazzo R, Cortese R, Bianchi E, Pessi A. Ingallinella P, et al. Among authors: bazzo r. Biochemistry. 2002 Apr 30;41(17):5483-92. doi: 10.1021/bi025603x. Biochemistry. 2002. PMID: 11969409

3

Measurement of homonuclear three-bond J(H(N)Halpha) coupling constants in unlabeled peptides complexed with labeled proteins: application to a decapeptide inhibitor bound to the proteinase domain of the NS3 protein of hepatitis C virus (HCV).

Cicero DO, Barbato G, Koch U, Ingallinella P, Bianchi E, Sambucini S, Neddermann P, De Francesco R, Pessi A, Bazzo R. Cicero DO, et al. Among authors: bazzo r. J Biomol NMR. 2001 May;20(1):23-9. doi: 10.1023/a:1011281527761. J Biomol NMR. 2001. PMID: 11430752

4

Binding of a noncovalent inhibitor exploiting the S' region stabilizes the hepatitis C virus NS3 protease conformation in the absence of cofactor.

Gallo M, Pennestri M, Bottomley MJ, Barbato G, Eliseo T, Paci M, Narjes F, De Francesco R, Summa V, Koch U, Bazzo R, Cicero DO. Gallo M, et al. Among authors: bazzo r. J Mol Biol. 2009 Jan 30;385(4):1142-55. doi: 10.1016/j.jmb.2008.11.017. Epub 2008 Nov 24. J Mol Biol. 2009. PMID: 19061898

5

Inhibitor binding induces active site stabilization of the HCV NS3 protein serine protease domain.

Barbato G, Cicero DO, Cordier F, Narjes F, Gerlach B, Sambucini S, Grzesiek S, Matassa VG, De Francesco R, Bazzo R. Barbato G, et al. Among authors: bazzo r. EMBO J. 2000 Mar 15;19(6):1195-206. doi: 10.1093/emboj/19.6.1195. EMBO J. 2000. PMID: 10716920 Free PMC article.

6

Structural characterization of the Hepatitis C Virus NS3 protease from genotype 3a: the basis of the genotype 1b vs. 3a inhibitor potency shift.

Gallo M, Bottomley MJ, Pennestri M, Eliseo T, Paci M, Koch U, Bazzo R, Summa V, Carfì A, Cicero DO. Gallo M, et al. Among authors: bazzo r. Virology. 2010 Sep 30;405(2):424-38. doi: 10.1016/j.virol.2010.05.035. Epub 2010 Jul 13. Virology. 2010. PMID: 20630554 Free article.

7

Structural characterization of the interactions of optimized product inhibitors with the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein by NMR and modelling studies.

Cicero DO, Barbato G, Koch U, Ingallinella P, Bianchi E, Nardi MC, Steinkühler C, Cortese R, Matassa V, De Francesco R, Pessi A, Bazzo R. Cicero DO, et al. Among authors: bazzo r. J Mol Biol. 1999 Jun 4;289(2):385-96. doi: 10.1006/jmbi.1999.2746. J Mol Biol. 1999. PMID: 10366512

8

Molecular insights into quorum sensing in the human pathogen Pseudomonas aeruginosa from the structure of the virulence regulator LasR bound to its autoinducer.

Bottomley MJ, Muraglia E, Bazzo R, Carfì A. Bottomley MJ, et al. Among authors: bazzo r. J Biol Chem. 2007 May 4;282(18):13592-600. doi: 10.1074/jbc.M700556200. Epub 2007 Mar 15. J Biol Chem. 2007. PMID: 17363368 Free article.

9

The metal binding site of the hepatitis C virus NS3 protease. A spectroscopic investigation.

Urbani A, Bazzo R, Nardi MC, Cicero DO, De Francesco R, Steinkühler C, Barbato G. Urbani A, et al. Among authors: bazzo r. J Biol Chem. 1998 Jul 24;273(30):18760-9. doi: 10.1074/jbc.273.30.18760. J Biol Chem. 1998. PMID: 9668049 Free article.

10

High-resolution solution structure of two members of a conformationally homogeneous combinatorial peptide library based on the classical zinc-finger motif.

Barbato G, Cicero DO, Bianchi E, Pessi A, Bazzo R. Barbato G, et al. Among authors: bazzo r. J Biomol NMR. 1996 Jul;8(1):36-48. doi: 10.1007/BF00198138. J Biomol NMR. 1996. PMID: 8810524

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