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An affinity-enhanced neutralizing antibody against the membrane-proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10.
Nelson JD, Brunel FM, Jensen R, Crooks ET, Cardoso RM, Wang M, Hessell A, Wilson IA, Binley JM, Dawson PE, Burton DR, Zwick MB. Nelson JD, et al. Among authors: dawson pe. J Virol. 2007 Apr;81(8):4033-43. doi: 10.1128/JVI.02588-06. Epub 2007 Feb 7. J Virol. 2007. PMID: 17287272 Free PMC article.
Antibody elicited against the gp41 N-heptad repeat (NHR) coiled-coil can neutralize HIV-1 with modest potency but non-neutralizing antibodies also bind to NHR mimetics.
Nelson JD, Kinkead H, Brunel FM, Leaman D, Jensen R, Louis JM, Maruyama T, Bewley CA, Bowdish K, Clore GM, Dawson PE, Frederickson S, Mage RG, Richman DD, Burton DR, Zwick MB. Nelson JD, et al. Among authors: dawson pe. Virology. 2008 Jul 20;377(1):170-83. doi: 10.1016/j.virol.2008.04.005. Epub 2008 May 21. Virology. 2008. PMID: 18499210 Free PMC article.
218 results