Li P - Search Results

1

Novel 1-aminoethyl-3-arylsulfonyl-1H-pyrrolo[2,3-b]pyridines are potent 5-HT(6) agonists.

Bernotas RC, Lenicek S, Antane S, Cole DC, Harrison BL, Robichaud AJ, Zhang GM, Smith D, Platt B, Lin Q, Li P, Coupet J, Rosenzweig-Lipson S, Beyer CE, Schechter LE. Bernotas RC, et al. Among authors: li p. Bioorg Med Chem. 2009 Jul 15;17(14):5153-63. doi: 10.1016/j.bmc.2009.05.055. Epub 2009 May 29. Bioorg Med Chem. 2009. PMID: 19523834

2

Potent and novel 11β-HSD1 inhibitors identified from shape and docking based virtual screening.

Xia G, Xue M, Liu L, Yu J, Liu H, Li P, Wang J, Li Y, Xiong B, Shen J. Xia G, et al. Among authors: li y, li p. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5739-44. doi: 10.1016/j.bmcl.2011.08.019. Epub 2011 Aug 8. Bioorg Med Chem Lett. 2011. PMID: 21873057

3

Elaborate Structural Modifications Yielding Novel Boron-Containing N-Substituted Oseltamivir Derivatives as Potent Neuraminidase Inhibitors with Significantly Improved Broad-Spectrum Antiresistance Profiles.

Zhang J, Jia R, Jia H, Li P, Jiang Y, Bonomini A, Bertagnin C, Xu Q, Tan Z, Ma X, Loregian A, Huang B, Liu X, Zhan P. Zhang J, et al. Among authors: li p. J Med Chem. 2024 Dec 26;67(24):22191-22217. doi: 10.1021/acs.jmedchem.4c02222. Epub 2024 Dec 7. J Med Chem. 2024. PMID: 39644238

4

Design, synthesis and SAR of piperidyl-oxadiazoles as 11β-hydroxysteroid dehydrogenase 1 inhibitors.

Xia G, You X, Liu L, Liu H, Wang J, Shi Y, Li P, Xiong B, Liu X, Shen J. Xia G, et al. Among authors: li p. Eur J Med Chem. 2013 Apr;62:1-10. doi: 10.1016/j.ejmech.2012.12.059. Epub 2013 Jan 10. Eur J Med Chem. 2013. PMID: 23353742

5

Discovery of novel chalcone-dithiocarbamates as ROS-mediated apoptosis inducers by inhibiting catalase.

Fu DJ, Li JH, Yang JJ, Li P, Zhang YB, Liu S, Li ZR, Zhang SY. Fu DJ, et al. Among authors: li jh, li zr, li p. Bioorg Chem. 2019 May;86:375-385. doi: 10.1016/j.bioorg.2019.01.023. Epub 2019 Jan 16. Bioorg Chem. 2019. PMID: 30763884

6

A chemical tuned strategy to develop novel irreversible EGFR-TK inhibitors with improved safety and pharmacokinetic profiles.

Xia G, Chen W, Zhang J, Shao J, Zhang Y, Huang W, Zhang L, Qi W, Sun X, Li B, Xiang Z, Ma C, Xu J, Deng H, Li Y, Li P, Miao H, Han J, Liu Y, Shen J, Yu Y. Xia G, et al. Among authors: li y, li b, li p. J Med Chem. 2014 Dec 11;57(23):9889-900. doi: 10.1021/jm5014659. Epub 2014 Dec 1. J Med Chem. 2014. PMID: 25409491

7

Novel Derivative of Bardoxolone Methyl Improves Safety for the Treatment of Diabetic Nephropathy.

Huang Z, Mou Y, Xu X, Zhao D, Lai Y, Xu Y, Chen C, Li P, Peng S, Tian J, Zhang Y. Huang Z, et al. Among authors: li p. J Med Chem. 2017 Nov 9;60(21):8847-8857. doi: 10.1021/acs.jmedchem.7b00971. Epub 2017 Oct 19. J Med Chem. 2017. PMID: 28994286

8

Bioactive heterocycles containing a 3,4,5-trimethoxyphenyl fragment exerting potent antiproliferative activity through microtubule destabilization.

Fu DJ, Yang JJ, Li P, Hou YH, Huang SN, Tippin MA, Pham V, Song L, Zi X, Xue WL, Zhang LR, Zhang SY. Fu DJ, et al. Among authors: li p. Eur J Med Chem. 2018 Sep 5;157:50-61. doi: 10.1016/j.ejmech.2018.07.060. Epub 2018 Jul 29. Eur J Med Chem. 2018. PMID: 30075402

9

Discovery of Preclinical Candidate AD1058 as a Highly Potent, Selective, and Brain-Penetrant ATR Inhibitor for the Treatment of Advanced Malignancies.

Liu Z, Jiang K, Liu Y, Li J, Huang S, Li P, Xu L, Xu X, Hu X, Zeng X, Huang Z, Zhou Y, Li J, Long K, Wang M. Liu Z, et al. Among authors: li j, li p. J Med Chem. 2024 Aug 8;67(15):12735-12759. doi: 10.1021/acs.jmedchem.4c00734. Epub 2024 Jul 25. J Med Chem. 2024. PMID: 39053006

10

Discovery of 5,6-diaryl-1,2,4-triazines hybrids as potential apoptosis inducers.

Fu DJ, Song J, Hou YH, Zhao RH, Li JH, Mao RW, Yang JJ, Li P, Zi XL, Li ZH, Zhang QQ, Wang FY, Zhang SY, Zhang YB, Liu HM. Fu DJ, et al. Among authors: li jh, li zh, li p. Eur J Med Chem. 2017 Sep 29;138:1076-1088. doi: 10.1016/j.ejmech.2017.07.011. Epub 2017 Jul 8. Eur J Med Chem. 2017. PMID: 28763643 Free PMC article.

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