Zhang GM - Search Results

1

Novel 1-aminoethyl-3-arylsulfonyl-1H-pyrrolo[2,3-b]pyridines are potent 5-HT(6) agonists.

Bernotas RC, Lenicek S, Antane S, Cole DC, Harrison BL, Robichaud AJ, Zhang GM, Smith D, Platt B, Lin Q, Li P, Coupet J, Rosenzweig-Lipson S, Beyer CE, Schechter LE. Bernotas RC, et al. Among authors: zhang gm. Bioorg Med Chem. 2009 Jul 15;17(14):5153-63. doi: 10.1016/j.bmc.2009.05.055. Epub 2009 May 29. Bioorg Med Chem. 2009. PMID: 19523834

2

Discovery of N1-(6-chloroimidazo[2,1-b][1,3]thiazole-5-sulfonyl)tryptamine as a potent, selective, and orally active 5-HT(6) receptor agonist.

Cole DC, Stock JR, Lennox WJ, Bernotas RC, Ellingboe JW, Boikess S, Coupet J, Smith DL, Leung L, Zhang GM, Feng X, Kelly MF, Galante R, Huang P, Dawson LA, Marquis K, Rosenzweig-Lipson S, Beyer CE, Schechter LE. Cole DC, et al. Among authors: zhang gm. J Med Chem. 2007 Nov 15;50(23):5535-8. doi: 10.1021/jm070521y. Epub 2007 Oct 19. J Med Chem. 2007. PMID: 17948978

3

N1-arylsulfonyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole derivatives are potent and selective 5-HT6 receptor antagonists.

Cole DC, Ellingboe JW, Lennox WJ, Mazandarani H, Smith DL, Stock JR, Zhang G, Zhou P, Schechter LE. Cole DC, et al. Bioorg Med Chem Lett. 2005 Jan 17;15(2):379-83. doi: 10.1016/j.bmcl.2004.10.064. Bioorg Med Chem Lett. 2005. PMID: 15603958

4

Discovery of 5-arylsulfonamido-3-(pyrrolidin-2-ylmethyl)-1H-indole derivatives as potent, selective 5-HT6 receptor agonists and antagonists.

Cole DC, Lennox WJ, Lombardi S, Ellingboe JW, Bernotas RC, Tawa GJ, Mazandarani H, Smith DL, Zhang G, Coupet J, Schechter LE. Cole DC, et al. J Med Chem. 2005 Jan 27;48(2):353-6. doi: 10.1021/jm049243i. J Med Chem. 2005. PMID: 15658848

5

Conformationally constrained N1-arylsulfonyltryptamine derivatives as 5-HT6 receptor antagonists.

Cole DC, Lennox WJ, Stock JR, Ellingboe JW, Mazandarani H, Smith DL, Zhang G, Tawa GJ, Schechter LE. Cole DC, et al. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4780-5. doi: 10.1016/j.bmcl.2005.07.028. Bioorg Med Chem Lett. 2005. PMID: 16125933

6

Neuropharmacological profile of novel and selective 5-HT6 receptor agonists: WAY-181187 and WAY-208466.

Schechter LE, Lin Q, Smith DL, Zhang G, Shan Q, Platt B, Brandt MR, Dawson LA, Cole D, Bernotas R, Robichaud A, Rosenzweig-Lipson S, Beyer CE. Schechter LE, et al. Neuropsychopharmacology. 2008 May;33(6):1323-35. doi: 10.1038/sj.npp.1301503. Epub 2007 Jul 11. Neuropsychopharmacology. 2008. PMID: 17625499

7

1-(2-Aminoethyl)-3-(arylsulfonyl)-1H-indoles as novel 5-HT6 receptor ligands.

Bernotas R, Lenicek S, Antane S, Zhang GM, Smith D, Coupet J, Harrison B, Schechter LE. Bernotas R, et al. Among authors: zhang gm. Bioorg Med Chem Lett. 2004 Nov 15;14(22):5499-502. doi: 10.1016/j.bmcl.2004.09.003. Bioorg Med Chem Lett. 2004. PMID: 15482912

8

4-(2-Aminoethoxy)-N-(phenylsulfonyl)indoles as novel 5-HT6 receptor ligands.

Zhou P, Yan Y, Bernotas R, Harrison BL, Huryn D, Robichaud AJ, Zhang GM, Smith DL, Schechter LE. Zhou P, et al. Among authors: zhang gm. Bioorg Med Chem Lett. 2005 Mar 1;15(5):1393-6. doi: 10.1016/j.bmcl.2005.01.005. Bioorg Med Chem Lett. 2005. PMID: 15713394

9

Novel 1-(azacyclyl)-3-arylsulfonyl-1H-pyrrolo[2,3-b]pyridines as 5-HT6 agonists and antagonists.

Elokdah H, Li D, McFarlane G, Bernotas RC, Robichaud AJ, Magolda RL, Zhang GM, Smith D, Schechter LE. Elokdah H, et al. Among authors: zhang gm. Bioorg Med Chem. 2007 Sep 15;15(18):6208-26. doi: 10.1016/j.bmc.2007.06.024. Epub 2007 Jun 14. Bioorg Med Chem. 2007. PMID: 17624788

10

A regiospecific synthesis of a series of 1-sulfonyl azepinoindoles as potent 5-HT6 ligands.

Liu KG, Lo JR, Comery TA, Zhang GM, Zhang JY, Kowal DM, Smith DL, Di L, Kerns EH, Schechter LE, Robichaud AJ. Liu KG, et al. Among authors: zhang gm, zhang jy. Bioorg Med Chem Lett. 2008 Jul 15;18(14):3929-31. doi: 10.1016/j.bmcl.2008.06.030. Epub 2008 Jun 13. Bioorg Med Chem Lett. 2008. PMID: 18583130

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