Spehlmann ME - Search Results

1

Nuclear factor-kappa B in intestinal protection and destruction.

Spehlmann ME, Eckmann L. Spehlmann ME, et al. Curr Opin Gastroenterol. 2009 Mar;25(2):92-9. doi: 10.1097/MOG.0b013e328324f857. Curr Opin Gastroenterol. 2009. PMID: 19528876 Review.

2

Constitutive intestinal NF-κB does not trigger destructive inflammation unless accompanied by MAPK activation.

Guma M, Stepniak D, Shaked H, Spehlmann ME, Shenouda S, Cheroutre H, Vicente-Suarez I, Eckmann L, Kagnoff MF, Karin M. Guma M, et al. Among authors: spehlmann me. J Exp Med. 2011 Aug 29;208(9):1889-900. doi: 10.1084/jem.20110242. Epub 2011 Aug 8. J Exp Med. 2011. PMID: 21825016 Free PMC article.

3

IL-6-dependent mucosal protection prevents establishment of a microbial niche for attaching/effacing lesion-forming enteric bacterial pathogens.

Dann SM, Spehlmann ME, Hammond DC, Iimura M, Hase K, Choi LJ, Hanson E, Eckmann L. Dann SM, et al. Among authors: spehlmann me. J Immunol. 2008 May 15;180(10):6816-26. doi: 10.4049/jimmunol.180.10.6816. J Immunol. 2008. PMID: 18453602 Free PMC article.

4

CXCR2-dependent mucosal neutrophil influx protects against colitis-associated diarrhea caused by an attaching/effacing lesion-forming bacterial pathogen.

Spehlmann ME, Dann SM, Hruz P, Hanson E, McCole DF, Eckmann L. Spehlmann ME, et al. J Immunol. 2009 Sep 1;183(5):3332-43. doi: 10.4049/jimmunol.0900600. Epub 2009 Aug 12. J Immunol. 2009. PMID: 19675161 Free PMC article.

5

Coordinate down-regulation of adenylyl cyclase isoforms and the stimulatory G protein (G(s)) in intestinal epithelial cell differentiation.

Choi LJ, Jenikova G, Hanson E, Spehlmann ME, Boehling NS, Kirstein SL, Bundey RA, Smith JR, Insel PA, Eckmann L. Choi LJ, et al. Among authors: spehlmann me. J Biol Chem. 2010 Apr 23;285(17):12504-11. doi: 10.1074/jbc.M109.059741. Epub 2010 Feb 15. J Biol Chem. 2010. PMID: 20157112 Free PMC article.

6

Trp53 deficiency protects against acute intestinal inflammation.

Spehlmann ME, Manthey CF, Dann SM, Hanson E, Sandhu SS, Liu LY, Abdelmalak FK, Diamanti MA, Retzlaff K, Scheller J, Rose-John S, Greten FR, Wang JY, Eckmann L. Spehlmann ME, et al. J Immunol. 2013 Jul 15;191(2):837-47. doi: 10.4049/jimmunol.1201716. Epub 2013 Jun 14. J Immunol. 2013. PMID: 23772033 Free PMC article.

7

Activin and TGFβ use diverging mitogenic signaling in advanced colon cancer.

Bauer J, Ozden O, Akagi N, Carroll T, Principe DR, Staudacher JJ, Spehlmann ME, Eckmann L, Grippo PJ, Jung B. Bauer J, et al. Among authors: spehlmann me. Mol Cancer. 2015 Oct 24;14:182. doi: 10.1186/s12943-015-0456-4. Mol Cancer. 2015. PMID: 26497569 Free PMC article.

8

Natalizumab for the treatment of active Crohn's disease: results of the ENCORE Trial.

Targan SR, Feagan BG, Fedorak RN, Lashner BA, Panaccione R, Present DH, Spehlmann ME, Rutgeerts PJ, Tulassay Z, Volfova M, Wolf DC, Hernandez C, Bornstein J, Sandborn WJ; International Efficacy of Natalizumab in Crohn's Disease Response and Remission (ENCORE) Trial Group. Targan SR, et al. Among authors: spehlmann me. Gastroenterology. 2007 May;132(5):1672-83. doi: 10.1053/j.gastro.2007.03.024. Epub 2007 Mar 21. Gastroenterology. 2007. PMID: 17484865 Clinical Trial.

9

Absence of RNase H2 triggers generation of immunogenic micronuclei removed by autophagy.

Bartsch K, Knittler K, Borowski C, Rudnik S, Damme M, Aden K, Spehlmann ME, Frey N, Saftig P, Chalaris A, Rabe B. Bartsch K, et al. Among authors: spehlmann me. Hum Mol Genet. 2017 Oct 15;26(20):3960-3972. doi: 10.1093/hmg/ddx283. Hum Mol Genet. 2017. PMID: 29016854

10

Twin study indicates loss of interaction between microbiota and mucosa of patients with ulcerative colitis.

Lepage P, Häsler R, Spehlmann ME, Rehman A, Zvirbliene A, Begun A, Ott S, Kupcinskas L, Doré J, Raedler A, Schreiber S. Lepage P, et al. Among authors: spehlmann me. Gastroenterology. 2011 Jul;141(1):227-36. doi: 10.1053/j.gastro.2011.04.011. Epub 2011 Apr 16. Gastroenterology. 2011. PMID: 21621540

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