Mabondzo A - Search Results

1

ADDME--Avoiding Drug Development Mistakes Early: central nervous system drug discovery perspective.

Tsaioun K, Bottlaender M, Mabondzo A; Alzheimer's Drug Discovery Foundation. Tsaioun K, et al. Among authors: mabondzo a. BMC Neurol. 2009 Jun 12;9 Suppl 1(Suppl 1):S1. doi: 10.1186/1471-2377-9-S1-S1. BMC Neurol. 2009. PMID: 19534730 Free PMC article. Review.

2

Validation of in vitro cell-based human blood-brain barrier model using clinical positron emission tomography radioligands to predict in vivo human brain penetration.

Mabondzo A, Bottlaender M, Guyot AC, Tsaouin K, Deverre JR, Balimane PV. Mabondzo A, et al. Mol Pharm. 2010 Oct 4;7(5):1805-15. doi: 10.1021/mp1002366. Epub 2010 Sep 15. Mol Pharm. 2010. PMID: 20795735

3

In vitro primary human and animal cell-based blood-brain barrier models as a screening tool in drug discovery.

Lacombe O, Videau O, Chevillon D, Guyot AC, Contreras C, Blondel S, Nicolas L, Ghettas A, Bénech H, Thevenot E, Pruvost A, Bolze S, Krzaczkowski L, Prévost C, Mabondzo A. Lacombe O, et al. Among authors: mabondzo a. Mol Pharm. 2011 Jun 6;8(3):651-63. doi: 10.1021/mp1004614. Epub 2011 Apr 15. Mol Pharm. 2011. PMID: 21438632

4

Proof-of-Concept Study of Drug Brain Permeability Between in Vivo Human Brain and an in Vitro iPSCs-Human Blood-Brain Barrier Model.

Roux GL, Jarray R, Guyot AC, Pavoni S, Costa N, Théodoro F, Nassor F, Pruvost A, Tournier N, Kiyan Y, Langer O, Yates F, Deslys JP, Mabondzo A. Roux GL, et al. Among authors: mabondzo a. Sci Rep. 2019 Nov 5;9(1):16310. doi: 10.1038/s41598-019-52213-6. Sci Rep. 2019. PMID: 31690750 Free PMC article.

5

Combination of tenofovir and emtricitabine plus efavirenz: in vitro modulation of ABC transporter and intracellular drug accumulation.

Bousquet L, Pruvost A, Guyot AC, Farinotti R, Mabondzo A. Bousquet L, et al. Among authors: mabondzo a. Antimicrob Agents Chemother. 2009 Mar;53(3):896-902. doi: 10.1128/AAC.00733-08. Epub 2008 Dec 15. Antimicrob Agents Chemother. 2009. PMID: 19075072 Free PMC article.

6

P-glycoprotein, breast cancer resistance protein, Organic Anion Transporter 3, and Transporting Peptide 1a4 during blood-brain barrier maturation: involvement of Wnt/β-catenin and endothelin-1 signaling.

Harati R, Benech H, Villégier AS, Mabondzo A. Harati R, et al. Among authors: mabondzo a. Mol Pharm. 2013 May 6;10(5):1566-80. doi: 10.1021/mp300334r. Epub 2012 Oct 12. Mol Pharm. 2013. PMID: 22998451

7

Exposure to vehicle emissions results in altered blood brain barrier permeability and expression of matrix metalloproteinases and tight junction proteins in mice.

Oppenheim HA, Lucero J, Guyot AC, Herbert LM, McDonald JD, Mabondzo A, Lund AK. Oppenheim HA, et al. Among authors: mabondzo a. Part Fibre Toxicol. 2013 Dec 17;10:62. doi: 10.1186/1743-8977-10-62. Part Fibre Toxicol. 2013. PMID: 24344990 Free PMC article.

8

Endothelin-1 reduces p-glycoprotein transport activity in an in vitro model of human adult blood-brain barrier.

Hembury A, Mabondzo A. Hembury A, et al. Among authors: mabondzo a. Cell Mol Neurobiol. 2008 Nov;28(7):915-21. doi: 10.1007/s10571-008-9277-y. Epub 2008 Apr 1. Cell Mol Neurobiol. 2008. PMID: 18379872

9

Small-molecule induction of Aβ-42 peptide production in human cerebral organoids to model Alzheimer's disease associated phenotypes.

Pavoni S, Jarray R, Nassor F, Guyot AC, Cottin S, Rontard J, Mikol J, Mabondzo A, Deslys JP, Yates F. Pavoni S, et al. Among authors: mabondzo a. PLoS One. 2018 Dec 17;13(12):e0209150. doi: 10.1371/journal.pone.0209150. eCollection 2018. PLoS One. 2018. PMID: 30557391 Free PMC article.

10

A Small Compound Targeting Prohibitin with Potential Interest for Cognitive Deficit Rescue in Aging mice and Tau Pathology Treatment.

Guyot AC, Leuxe C, Disdier C, Oumata N, Costa N, Roux GL, Varela PF, Duchon A, Charbonnier JB, Herault Y, Pavoni S, Galons H, Andriambeloson E, Wagner S, Meijer L, Lund AK, Mabondzo A. Guyot AC, et al. Among authors: mabondzo a. Sci Rep. 2020 Jan 24;10(1):1143. doi: 10.1038/s41598-020-57560-3. Sci Rep. 2020. PMID: 31980673 Free PMC article.

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