Sebastian A - Search Results

1

Synthesis and structure-activity relationships of a novel series of non-peptide angiotensin II receptor binding inhibitors specific for the AT2 subtype.

Blankley CJ, Hodges JC, Klutchko SR, Himmelsbach RJ, Chucholowski A, Connolly CJ, Neergaard SJ, Van Nieuwenhze MS, Sebastian A, Quin J 3rd, et al. Blankley CJ, et al. Among authors: sebastian a. J Med Chem. 1991 Nov;34(11):3248-60. doi: 10.1021/jm00115a014. J Med Chem. 1991. PMID: 1956044

2

14 beta-[(p-nitrocinnamoyl)amino]morphinones, 14 beta-[(p-nitrocinnamoyl)amino]-7,8-dihydromorphinones, and their codeinone analogues: synthesis and receptor activity.

Sebastian A, Bidlack JM, Jiang Q, Deecher D, Teitler M, Glick SD, Archer S. Sebastian A, et al. J Med Chem. 1993 Oct 15;36(21):3154-60. doi: 10.1021/jm00073a015. J Med Chem. 1993. PMID: 7693944

3

Asymmetric syntheses, opioid receptor affinities, and antinociceptive effects of 8-amino-5,9-methanobenzocyclooctenes, a new class of structural analogues of the morphine alkaloids.

Schultz AG, Wang A, Alva C, Sebastian A, Glick SD, Deecher DC, Bidlack JM. Schultz AG, et al. Among authors: sebastian a. J Med Chem. 1996 May 10;39(10):1956-66. doi: 10.1021/jm950817g. J Med Chem. 1996. PMID: 8642554

4

Design, synthesis, and biological evaluation of a new series of pyrazole derivatives: Discovery of potent and selective JNK3 kinase inhibitors.

Abu Rabah RR, Sebastian A, Vunnam S, Sultan S, Tarazi H, Anbar HS, Shehata MK, Zaraei SO, Elgendy SM, Al Shamma SA, Omar HA, Al-Tel TH, El-Gamal MI. Abu Rabah RR, et al. Among authors: sebastian a. Bioorg Med Chem. 2022 Sep 1;69:116894. doi: 10.1016/j.bmc.2022.116894. Epub 2022 Jun 20. Bioorg Med Chem. 2022. PMID: 35764033

5

Design, synthesis, biological evaluation, and in silico studies of novel pyridopyridine derivatives as anticancer candidates targeting FMS kinase.

Sebastian A, Abu Rabah RR, Zaraei SO, Vunnam S, Sultan S, Anbar HS, El-Gamal R, Tarazi H, Sarg N, Alhamad DW, Al Shamma SA, Shahin AI, Omar HA, Al-Tel TH, El-Gamal MI. Sebastian A, et al. Eur J Med Chem. 2024 Aug 5;274:116557. doi: 10.1016/j.ejmech.2024.116557. Epub 2024 Jun 1. Eur J Med Chem. 2024. PMID: 38850857

6

Camptothecin's journey from discovery to WHO Essential Medicine: Fifty years of promise.

Khaiwa N, Maarouf NR, Darwish MH, Alhamad DWM, Sebastian A, Hamad M, Omar HA, Orive G, Al-Tel TH. Khaiwa N, et al. Among authors: sebastian a. Eur J Med Chem. 2021 Nov 5;223:113639. doi: 10.1016/j.ejmech.2021.113639. Epub 2021 Jun 17. Eur J Med Chem. 2021. PMID: 34175539 Review.

7

5 beta-Methyl-14 beta-(p-nitrocinnamoylamino)-7,8-dihydromorphinone and its corresponding N-cyclopropylmethyl analog, N-cyclopropylmethylnor-5 beta-methyl-14 beta-(p-nitrocinnamoylamino)- 7,8-dihydromorphinone: mu-selective irreversible opioid antagonists.

Jiang Q, Sebastian A, Archer S, Bidlack JM. Jiang Q, et al. Among authors: sebastian a. J Pharmacol Exp Ther. 1994 Mar;268(3):1107-13. J Pharmacol Exp Ther. 1994. PMID: 7511163

8

5 beta-Methyl-14 beta-(p-nitrocinnamoylamino)-7,8-dihydromorphinone: a long-lasting mu-opioid receptor antagonist devoid of agonist properties.

Jiang Q, Sebastian A, Archer S, Bidlack JM. Jiang Q, et al. Among authors: sebastian a. Eur J Pharmacol. 1993 Jan 5;230(1):129-30. doi: 10.1016/0014-2999(93)90423-f. Eur J Pharmacol. 1993. PMID: 7679076 Free article.

9

Preventing morphine antinociceptive tolerance by irreversible mu opioid antagonists before the onset of their antagonism.

Jiang Q, Seyed-Mozaffari A, Sebastian A, Archer S, Bidlack JM. Jiang Q, et al. Among authors: sebastian a. J Pharmacol Exp Ther. 1995 May;273(2):680-8. J Pharmacol Exp Ther. 1995. PMID: 7752070

10

Metopon and two unique derivatives: affinity and selectivity for the multiple opioid receptors.

McLaughlin JP, Nowak D, Sebastian A, Schultz AG, Archer S, Bidlack JM. McLaughlin JP, et al. Among authors: sebastian a. Eur J Pharmacol. 1995 Dec 27;294(1):201-6. doi: 10.1016/0014-2999(95)00536-6. Eur J Pharmacol. 1995. PMID: 8788432 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

912 results

Search Page

Filters