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Heavy chain-only antibodies are spontaneously produced in light chain-deficient mice.
Zou X, Osborn MJ, Bolland DJ, Smith JA, Corcos D, Hamon M, Oxley D, Hutchings A, Morgan G, Santos F, Kilshaw PJ, Taussig MJ, Corcoran AE, Brüggemann M. Zou X, et al. Among authors: oxley d. J Exp Med. 2007 Dec 24;204(13):3271-83. doi: 10.1084/jem.20071155. Epub 2007 Dec 17. J Exp Med. 2007. PMID: 18086860 Free PMC article.
PI3Kβ plays a critical role in neutrophil activation by immune complexes.
Kulkarni S, Sitaru C, Jakus Z, Anderson KE, Damoulakis G, Davidson K, Hirose M, Juss J, Oxley D, Chessa TA, Ramadani F, Guillou H, Segonds-Pichon A, Fritsch A, Jarvis GE, Okkenhaug K, Ludwig R, Zillikens D, Mocsai A, Vanhaesebroeck B, Stephens LR, Hawkins PT. Kulkarni S, et al. Among authors: oxley d. Sci Signal. 2011 Apr 12;4(168):ra23. doi: 10.1126/scisignal.2001617. Sci Signal. 2011. PMID: 21487106
Quantitation of class IA PI3Ks in mice reveals p110-free-p85s and isoform-selective subunit associations and recruitment to receptors.
Tsolakos N, Durrant TN, Chessa T, Suire SM, Oxley D, Kulkarni S, Downward J, Perisic O, Williams RL, Stephens L, Hawkins PT. Tsolakos N, et al. Among authors: oxley d. Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):12176-12181. doi: 10.1073/pnas.1803446115. Epub 2018 Nov 15. Proc Natl Acad Sci U S A. 2018. PMID: 30442661 Free PMC article.
175 results