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WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4.
Chávez-Canales M, Zhang C, Soukaseum C, Moreno E, Pacheco-Alvarez D, Vidal-Petiot E, Castañeda-Bueno M, Vázquez N, Rojas-Vega L, Meermeier NP, Rogers S, Jeunemaitre X, Yang CL, Ellison DH, Gamba G, Hadchouel J. Chávez-Canales M, et al. Among authors: ellison dh. Hypertension. 2014 Nov;64(5):1047-53. doi: 10.1161/HYPERTENSIONAHA.114.04036. Epub 2014 Aug 11. Hypertension. 2014. PMID: 25113964 Free PMC article.
An Integrated View of Potassium Homeostasis.
Hoorn EJ, Loffing J, Ellison DH. Hoorn EJ, et al. Among authors: ellison dh. N Engl J Med. 2015 Oct 29;373(18):1786. doi: 10.1056/NEJMc1509656. N Engl J Med. 2015. PMID: 26510040 Free article. No abstract available.
C-terminally truncated, kidney-specific variants of the WNK4 kinase lack several sites that regulate its activity.
Murillo-de-Ozores AR, Rodríguez-Gama A, Bazúa-Valenti S, Leyva-Ríos K, Vázquez N, Pacheco-Álvarez D, De La Rosa-Velázquez IA, Wengi A, Stone KL, Zhang J, Loffing J, Lifton RP, Yang CL, Ellison DH, Gamba G, Castañeda-Bueno M. Murillo-de-Ozores AR, et al. Among authors: ellison dh. J Biol Chem. 2018 Aug 3;293(31):12209-12221. doi: 10.1074/jbc.RA118.003037. Epub 2018 Jun 19. J Biol Chem. 2018. PMID: 29921588 Free PMC article.
197 results