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Inhibitory effect of 6-formylpterin on HIF-1alpha protein accumulation.
Sommani P, Yamashita K, Miyoshi T, Tsunemine H, Kodaki T, Mori H, Hirota K, Arai T, Sasada M, Makino K. Sommani P, et al. Among authors: miyoshi t. Biol Pharm Bull. 2007 Nov;30(11):2181-4. doi: 10.1248/bpb.30.2181. Biol Pharm Bull. 2007. PMID: 17978497 Free article.
The radical scavenger edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one) reacts with a pterin derivative and produces a cytotoxic substance that induces intracellular reactive oxygen species generation and cell death.
Arai T, Nonogawa M, Makino K, Endo N, Mori H, Miyoshi T, Yamashita K, Sasada M, Kakuyama M, Fukuda K. Arai T, et al. Among authors: miyoshi t. J Pharmacol Exp Ther. 2008 Feb;324(2):529-38. doi: 10.1124/jpet.107.131391. Epub 2007 Nov 20. J Pharmacol Exp Ther. 2008. PMID: 18029546
Ozone production by amino acids contributes to killing of bacteria.
Yamashita K, Miyoshi T, Arai T, Endo N, Itoh H, Makino K, Mizugishi K, Uchiyama T, Sasada M. Yamashita K, et al. Among authors: miyoshi t. Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):16912-7. doi: 10.1073/pnas.0807952105. Epub 2008 Oct 29. Proc Natl Acad Sci U S A. 2008. PMID: 18971328 Free PMC article.
1,635 results