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Synergistic drug combinations tend to improve therapeutically relevant selectivity.
Lehár J, Krueger AS, Avery W, Heilbut AM, Johansen LM, Price ER, Rickles RJ, Short GF 3rd, Staunton JE, Jin X, Lee MS, Zimmermann GR, Borisy AA. Lehár J, et al. Among authors: zimmermann gr. Nat Biotechnol. 2009 Jul;27(7):659-66. doi: 10.1038/nbt.1549. Epub 2009 Jul 5. Nat Biotechnol. 2009. PMID: 19581876 Free PMC article.
Systematic discovery of multicomponent therapeutics.
Borisy AA, Elliott PJ, Hurst NW, Lee MS, Lehar J, Price ER, Serbedzija G, Zimmermann GR, Foley MA, Stockwell BR, Keith CT. Borisy AA, et al. Among authors: zimmermann gr. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7977-82. doi: 10.1073/pnas.1337088100. Epub 2003 Jun 10. Proc Natl Acad Sci U S A. 2003. PMID: 12799470 Free PMC article.
Chemical combination effects predict connectivity in biological systems.
Lehár J, Zimmermann GR, Krueger AS, Molnar RA, Ledell JT, Heilbut AM, Short GF 3rd, Giusti LC, Nolan GP, Magid OA, Lee MS, Borisy AA, Stockwell BR, Keith CT. Lehár J, et al. Among authors: zimmermann gr. Mol Syst Biol. 2007;3:80. doi: 10.1038/msb4100116. Epub 2007 Feb 27. Mol Syst Biol. 2007. PMID: 17332758 Free PMC article.
[Posterior meniscus root tears].
Balke M, Metzlaff S, Faber S, Niethammer T, Roessler PP, Henkelmann R, Diermeier T, Kurme A, Winkler PW, Colcuc S, Zimmermann GR, Petersen W. Balke M, et al. Among authors: zimmermann gr. Orthopade. 2021 Dec;50(12):1039-1050. doi: 10.1007/s00132-021-04192-8. Orthopade. 2021. PMID: 34767042 German.
15 results