Hauke J - Search Results

1

LBH589 induces up to 10-fold SMN protein levels by several independent mechanisms and is effective even in cells from SMA patients non-responsive to valproate.

Garbes L, Riessland M, Hölker I, Heller R, Hauke J, Tränkle C, Coras R, Blümcke I, Hahnen E, Wirth B. Garbes L, et al. Among authors: hauke j. Hum Mol Genet. 2009 Oct 1;18(19):3645-58. doi: 10.1093/hmg/ddp313. Epub 2009 Jul 7. Hum Mol Genet. 2009. PMID: 19584083

2

The peroxisome proliferator-activated receptor-gamma agonist troglitazone inhibits transforming growth factor-beta-mediated glioma cell migration and brain invasion.

Coras R, Hölsken A, Seufert S, Hauke J, Eyüpoglu IY, Reichel M, Tränkle C, Siebzehnrübl FA, Buslei R, Blümcke I, Hahnen E. Coras R, et al. Among authors: hauke j. Mol Cancer Ther. 2007 Jun;6(6):1745-54. doi: 10.1158/1535-7163.MCT-06-0763. Epub 2007 May 31. Mol Cancer Ther. 2007. PMID: 17541035

3

Histone deacetylase inhibitors: possible implications for neurodegenerative disorders.

Hahnen E, Hauke J, Tränkle C, Eyüpoglu IY, Wirth B, Blümcke I. Hahnen E, et al. Among authors: hauke j. Expert Opin Investig Drugs. 2008 Feb;17(2):169-84. doi: 10.1517/13543784.17.2.169. Expert Opin Investig Drugs. 2008. PMID: 18230051 Review.

4

Survival motor neuron gene 2 silencing by DNA methylation correlates with spinal muscular atrophy disease severity and can be bypassed by histone deacetylase inhibition.

Hauke J, Riessland M, Lunke S, Eyüpoglu IY, Blümcke I, El-Osta A, Wirth B, Hahnen E. Hauke J, et al. Hum Mol Genet. 2009 Jan 15;18(2):304-17. doi: 10.1093/hmg/ddn357. Epub 2008 Oct 29. Hum Mol Genet. 2009. PMID: 18971205 Free PMC article.

5

Increased reelin promoter methylation is associated with granule cell dispersion in human temporal lobe epilepsy.

Kobow K, Jeske I, Hildebrandt M, Hauke J, Hahnen E, Buslei R, Buchfelder M, Weigel D, Stefan H, Kasper B, Pauli E, Blümcke I. Kobow K, et al. Among authors: hauke j. J Neuropathol Exp Neurol. 2009 Apr;68(4):356-64. doi: 10.1097/NEN.0b013e31819ba737. J Neuropathol Exp Neurol. 2009. PMID: 19287316

6

SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy.

Riessland M, Ackermann B, Förster A, Jakubik M, Hauke J, Garbes L, Fritzsche I, Mende Y, Blumcke I, Hahnen E, Wirth B. Riessland M, et al. Among authors: hauke j. Hum Mol Genet. 2010 Apr 15;19(8):1492-506. doi: 10.1093/hmg/ddq023. Epub 2010 Jan 22. Hum Mol Genet. 2010. PMID: 20097677

7

Dissection of mitogenic and neurodegenerative actions of cystine and glutamate in malignant gliomas.

Savaskan NE, Seufert S, Hauke J, Tränkle C, Eyüpoglu IY, Hahnen E. Savaskan NE, et al. Among authors: hauke j. Oncogene. 2011 Jan 6;30(1):43-53. doi: 10.1038/onc.2010.391. Epub 2010 Aug 30. Oncogene. 2011. PMID: 20802520

8

Analysis of 30 putative BRCA1 splicing mutations in hereditary breast and ovarian cancer families identifies exonic splice site mutations that escape in silico prediction.

Wappenschmidt B, Becker AA, Hauke J, Weber U, Engert S, Köhler J, Kast K, Arnold N, Rhiem K, Hahnen E, Meindl A, Schmutzler RK. Wappenschmidt B, et al. Among authors: hauke j. PLoS One. 2012;7(12):e50800. doi: 10.1371/journal.pone.0050800. Epub 2012 Dec 11. PLoS One. 2012. PMID: 23239986 Free PMC article.

9

Deep sequencing reveals increased DNA methylation in chronic rat epilepsy.

Kobow K, Kaspi A, Harikrishnan KN, Kiese K, Ziemann M, Khurana I, Fritzsche I, Hauke J, Hahnen E, Coras R, Mühlebner A, El-Osta A, Blümcke I. Kobow K, et al. Among authors: hauke j. Acta Neuropathol. 2013 Nov;126(5):741-56. doi: 10.1007/s00401-013-1168-8. Epub 2013 Sep 5. Acta Neuropathol. 2013. PMID: 24005891 Free PMC article.

10

A novel large in-frame deletion within the CACNA1F gene associates with a cone-rod dystrophy 3-like phenotype.

Hauke J, Schild A, Neugebauer A, Lappa A, Fricke J, Fauser S, Rösler S, Pannes A, Zarrinnam D, Altmüller J, Motameny S, Nürnberg G, Nürnberg P, Hahnen E, Beck BB. Hauke J, et al. PLoS One. 2013 Oct 4;8(10):e76414. doi: 10.1371/journal.pone.0076414. eCollection 2013. PLoS One. 2013. PMID: 24124559 Free PMC article.

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