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Failure to confirm allelic and haplotypic association between markers at the chromosome 6p22.3 dystrobrevin-binding protein 1 (DTNBP1) locus and schizophrenia.
Datta SR, McQuillin A, Puri V, Choudhury K, Thirumalai S, Lawrence J, Pimm J, Bass N, Lamb G, Moorey H, Morgan J, Punukollu B, Kandasami G, Kirwin S, Sule A, Quested D, Curtis D, Gurling HM. Datta SR, et al. Behav Brain Funct. 2007 Sep 23;3:50. doi: 10.1186/1744-9081-3-50. Behav Brain Funct. 2007. PMID: 17888175 Free PMC article.
A threonine to isoleucine missense mutation in the pericentriolar material 1 gene is strongly associated with schizophrenia.
Datta SR, McQuillin A, Rizig M, Blaveri E, Thirumalai S, Kalsi G, Lawrence J, Bass NJ, Puri V, Choudhury K, Pimm J, Crombie C, Fraser G, Walker N, Curtis D, Zvelebil M, Pereira A, Kandaswamy R, St Clair D, Gurling HM. Datta SR, et al. Mol Psychiatry. 2010 Jun;15(6):615-28. doi: 10.1038/mp.2008.128. Epub 2008 Dec 2. Mol Psychiatry. 2010. PMID: 19048012
Failure to confirm allelic association between markers at the CAPON gene locus and schizophrenia in a British sample.
Puri V, McQuillin A, Thirumalai S, Lawrence J, Krasucki R, Choudhury K, Datta S, Kerwin S, Quested D, Bass N, Pimm J, Lamb G, Moorey H, Kandasami G, Badacsonyi A, Kelly K, Morgan J, Punukollu B, Nadeem H, Curtis D, Gurling HM. Puri V, et al. Biol Psychiatry. 2006 Jan 15;59(2):195-7. doi: 10.1016/j.biopsych.2005.08.015. Epub 2005 Oct 3. Biol Psychiatry. 2006. PMID: 16202394 Clinical Trial.
Failure to confirm genetic association between schizophrenia and markers on chromosome 1q23.3 in the region of the gene encoding the regulator of G-protein signaling 4 protein (RGS4).
Rizig MA, McQuillin A, Puri V, Choudhury K, Datta S, Thirumalai S, Lawrence J, Quested D, Pimm J, Bass N, Lamb G, Moorey H, Badacsonyi A, Kelly K, Morgan J, Punukollu B, Kandasami G, Curtis D, Gurling H. Rizig MA, et al. Am J Med Genet B Neuropsychiatr Genet. 2006 Apr 5;141B(3):296-300. doi: 10.1002/ajmg.b.30288. Am J Med Genet B Neuropsychiatr Genet. 2006. PMID: 16508931
Fine mapping by genetic association implicates the chromosome 1q23.3 gene UHMK1, encoding a serine/threonine protein kinase, as a novel schizophrenia susceptibility gene.
Puri V, McQuillin A, Choudhury K, Datta S, Pimm J, Thirumalai S, Krasucki R, Lawrence J, Quested D, Bass N, Moorey H, Morgan J, Punukollu B, Kandasami G, Curtis D, Gurling H. Puri V, et al. Biol Psychiatry. 2007 Apr 1;61(7):873-9. doi: 10.1016/j.biopsych.2006.06.014. Epub 2006 Sep 15. Biol Psychiatry. 2007. PMID: 16978587
A genetic association study of chromosome 11q22-24 in two different samples implicates the FXYD6 gene, encoding phosphohippolin, in susceptibility to schizophrenia.
Choudhury K, McQuillin A, Puri V, Pimm J, Datta S, Thirumalai S, Krasucki R, Lawrence J, Bass NJ, Quested D, Crombie C, Fraser G, Walker N, Nadeem H, Johnson S, Curtis D, St Clair D, Gurling HM. Choudhury K, et al. Am J Hum Genet. 2007 Apr;80(4):664-72. doi: 10.1086/513475. Epub 2007 Mar 1. Am J Hum Genet. 2007. PMID: 17357072 Free PMC article.
Confirmation of the genetic association between the U2AF homology motif (UHM) kinase 1 (UHMK1) gene and schizophrenia on chromosome 1q23.3.
Puri V, McQuillin A, Datta S, Choudhury K, Pimm J, Thirumalai S, Krasucki R, Lawrence J, Quested D, Bass N, Crombie C, Fraser G, Walker N, Moorey H, Ray MK, Sule A, Curtis D, St Clair D, Gurling H. Puri V, et al. Eur J Hum Genet. 2008 Oct;16(10):1275-82. doi: 10.1038/ejhg.2008.76. Epub 2008 Apr 16. Eur J Hum Genet. 2008. PMID: 18414510
The Epsin 4 gene on chromosome 5q, which encodes the clathrin-associated protein enthoprotin, is involved in the genetic susceptibility to schizophrenia.
Pimm J, McQuillin A, Thirumalai S, Lawrence J, Quested D, Bass N, Lamb G, Moorey H, Datta SR, Kalsi G, Badacsonyi A, Kelly K, Morgan J, Punukollu B, Curtis D, Gurling H. Pimm J, et al. Among authors: datta sr. Am J Hum Genet. 2005 May;76(5):902-7. doi: 10.1086/430095. Epub 2005 Mar 25. Am J Hum Genet. 2005. PMID: 15793701 Free PMC article.
141 results