Laffan MA - Search Results

1

A novel binding site for ADAMTS13 constitutively exposed on the surface of globular VWF.

Zanardelli S, Chion AC, Groot E, Lenting PJ, McKinnon TA, Laffan MA, Tseng M, Lane DA. Zanardelli S, et al. Among authors: laffan ma. Blood. 2009 Sep 24;114(13):2819-28. doi: 10.1182/blood-2009-05-224915. Epub 2009 Jul 8. Blood. 2009. PMID: 19587373 Free PMC article.

2

Genetic and phenotypic variability between families with hereditary protein S deficiency.

Rezende SM, Lane DA, Zöller B, Mille-Baker B, Laffan M, Dahlbäck B, Simmonds RE. Rezende SM, et al. Thromb Haemost. 2002 Feb;87(2):258-65. doi: 10.1055/s-0037-1612982. Thromb Haemost. 2002. PMID: 11858485

3

Deletion or replacement of the second EGF-like domain of protein S results in loss of APC cofactor activity.

Mille-Baker B, Rezende SM, Simmonds RE, Mason PJ, Lane DA, Laffan MA. Mille-Baker B, et al. Among authors: laffan ma. Blood. 2003 Feb 15;101(4):1416-8. doi: 10.1182/blood-2002-08-2353. Epub 2002 Oct 10. Blood. 2003. PMID: 12393507 Free article.

4

Bombay phenotype is associated with reduced plasma-VWF levels and an increased susceptibility to ADAMTS13 proteolysis.

O'Donnell JS, McKinnon TA, Crawley JT, Lane DA, Laffan MA. O'Donnell JS, et al. Among authors: laffan ma. Blood. 2005 Sep 15;106(6):1988-91. doi: 10.1182/blood-2005-02-0792. Epub 2005 May 10. Blood. 2005. PMID: 15886321 Free article.

5

Proteolysis of the endothelial cell protein C receptor by neutrophil proteinase 3.

Villegas-Mendez A, Montes R, Ambrose LR, Warrens AN, Laffan M, Lane DA. Villegas-Mendez A, et al. J Thromb Haemost. 2007 May;5(5):980-8. doi: 10.1111/j.1538-7836.2007.02480.x. J Thromb Haemost. 2007. PMID: 17459006 Free PMC article.

6

N-linked glycosylation of VWF modulates its interaction with ADAMTS13.

McKinnon TA, Chion AC, Millington AJ, Lane DA, Laffan MA. McKinnon TA, et al. Among authors: laffan ma. Blood. 2008 Mar 15;111(6):3042-9. doi: 10.1182/blood-2007-06-095042. Epub 2007 Nov 1. Blood. 2008. PMID: 17975018 Free article.

7

A nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the alphaIIbbeta3 integrin and cosegregates dominantly with abnormal proplatelet formation and macrothrombocytopenia.

Ghevaert C, Salsmann A, Watkins NA, Schaffner-Reckinger E, Rankin A, Garner SF, Stephens J, Smith GA, Debili N, Vainchenker W, de Groot PG, Huntington JA, Laffan M, Kieffer N, Ouwehand WH. Ghevaert C, et al. Blood. 2008 Apr 1;111(7):3407-14. doi: 10.1182/blood-2007-09-112615. Epub 2007 Dec 7. Blood. 2008. PMID: 18065693 Free article.

8

Blocking von Willebrand factor: a novel anti-platelet therapy.

Laffan M, McKinnon TA. Laffan M, et al. J Thromb Haemost. 2009 Jul;7(7):1152-4. doi: 10.1111/j.1538-7836.2009.03480.x. Epub 2009 May 8. J Thromb Haemost. 2009. PMID: 19426284 Free article. No abstract available.

9

Characterization of W1745C and S1783A: 2 novel mutations causing defective collagen binding in the A3 domain of von Willebrand factor.

Riddell AF, Gomez K, Millar CM, Mellars G, Gill S, Brown SA, Sutherland M, Laffan MA, McKinnon TA. Riddell AF, et al. Among authors: laffan ma. Blood. 2009 Oct 15;114(16):3489-96. doi: 10.1182/blood-2008-10-184317. Epub 2009 Aug 17. Blood. 2009. PMID: 19687512 Free article.

10

The plasma von Willebrand factor O-glycome comprises a surprising variety of structures including ABH antigens and disialosyl motifs.

Canis K, McKinnon TA, Nowak A, Panico M, Morris HR, Laffan M, Dell A. Canis K, et al. J Thromb Haemost. 2010 Jan;8(1):137-45. doi: 10.1111/j.1538-7836.2009.03665.x. Epub 2009 Oct 24. J Thromb Haemost. 2010. PMID: 19874459 Free article.

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