Aalberse RC - Search Results

1

Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivo.

Labrijn AF, Buijsse AO, van den Bremer ET, Verwilligen AY, Bleeker WK, Thorpe SJ, Killestein J, Polman CH, Aalberse RC, Schuurman J, van de Winkel JG, Parren PW. Labrijn AF, et al. Among authors: aalberse rc. Nat Biotechnol. 2009 Aug;27(8):767-71. doi: 10.1038/nbt.1553. Epub 2009 Jul 20. Nat Biotechnol. 2009. PMID: 19620983

2

Mouse/human chimeric IgE antibodies directed to the house dust mite allergen Der p 2.

Schuurman J, Lourens TE, Perdok GJ, Parren PW, Aalberse RC. Schuurman J, et al. Among authors: aalberse rc. Int Arch Allergy Immunol. 1995 May-Jun;107(1-3):465-6. doi: 10.1159/000237085. Int Arch Allergy Immunol. 1995. PMID: 7613217 No abstract available.

3

Production of a mouse/human chimeric IgE monoclonal antibody to the house dust mite allergen Der p 2 and its use for the absolute quantification of allergen-specific IgE.

Schuurman J, Perdok GJ, Lourens TE, Parren PW, Chapman MD, Aalberse RC. Schuurman J, et al. Among authors: aalberse rc. J Allergy Clin Immunol. 1997 Apr;99(4):545-50. doi: 10.1016/s0091-6749(97)70083-6. J Allergy Clin Immunol. 1997. PMID: 9111501

4

Mouse/human chimeric antibodies directed to two nonoverlapping epitopes of the house dust mite allergen, Der p 2.

Schuurman J, Perdok GJ, Aalberse RC. Schuurman J, et al. Among authors: aalberse rc. Int Arch Allergy Immunol. 1997 May-Jul;113(1-3):262-3. doi: 10.1159/000237566. Int Arch Allergy Immunol. 1997. PMID: 9130542 No abstract available.

5

Complementation of Der P 2-induced histamine release from human basophils sensitized with monoclonal IgE: not only by IgE, but also by IgG antibodies directed to a nonoverlapping epitope of Der p 2.

Schuurman J, Perdok GJ, Mueller GA, Aalberse RC. Schuurman J, et al. Among authors: aalberse rc. J Allergy Clin Immunol. 1998 Mar;101(3):404-9. doi: 10.1016/S0091-6749(98)70255-6. J Allergy Clin Immunol. 1998. PMID: 9525459

6

Mouse/human chimeric IgG1 and IgG4 antibodies directed to the house dust mite allergen Der p 2: use in quantification of allergen specific IgG.

Schuurman J, Perdok GJ, Mueller GA, Benjamin DC, Yong Tan K, Chapman MD, Aalberse RC. Schuurman J, et al. Among authors: aalberse rc. Clin Exp Allergy. 1997 Sep;27(9):1095-102. doi: 10.1111/j.1365-2222.1997.tb01262.x. Clin Exp Allergy. 1997. PMID: 9678842

7

The apparent monovalency of human IgG4 is due to bispecificity.

Aalberse RC, Schuurman J, van Ree R. Aalberse RC, et al. Int Arch Allergy Immunol. 1999 Feb-Apr;118(2-4):187-9. doi: 10.1159/000024062. Int Arch Allergy Immunol. 1999. PMID: 10224373

8

Normal human immunoglobulin G4 is bispecific: it has two different antigen-combining sites.

Schuurman J, Van Ree R, Perdok GJ, Van Doorn HR, Tan KY, Aalberse RC. Schuurman J, et al. Among authors: aalberse rc. Immunology. 1999 Aug;97(4):693-8. doi: 10.1046/j.1365-2567.1999.00845.x. Immunology. 1999. PMID: 10457225 Free PMC article.

9

The inter-heavy chain disulfide bonds of IgG4 are in equilibrium with intra-chain disulfide bonds.

Schuurman J, Perdok GJ, Gorter AD, Aalberse RC. Schuurman J, et al. Among authors: aalberse rc. Mol Immunol. 2001 Jan;38(1):1-8. doi: 10.1016/s0161-5890(01)00050-5. Mol Immunol. 2001. PMID: 11483205

10

IgG4 breaking the rules.

Aalberse RC, Schuurman J. Aalberse RC, et al. Immunology. 2002 Jan;105(1):9-19. doi: 10.1046/j.0019-2805.2001.01341.x. Immunology. 2002. PMID: 11849310 Free PMC article. Review.

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