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SIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasis.
Cheng H, Liu P, Wang ZC, Zou L, Santiago S, Garbitt V, Gjoerup OV, Iglehart JD, Miron A, Richardson AL, Hahn WC, Zhao JJ. Cheng H, et al. Among authors: zhao jj. Sci Signal. 2009 Jul 21;2(80):ra35. doi: 10.1126/scisignal.2000369. Sci Signal. 2009. PMID: 19622832 Free PMC article.
Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1.
Cotsiki M, Lock RL, Cheng Y, Williams GL, Zhao J, Perera D, Freire R, Entwistle A, Golemis EA, Roberts TM, Jat PS, Gjoerup OV. Cotsiki M, et al. Proc Natl Acad Sci U S A. 2004 Jan 27;101(4):947-52. doi: 10.1073/pnas.0308006100. Epub 2004 Jan 19. Proc Natl Acad Sci U S A. 2004. PMID: 14732683 Free PMC article.
Surveillance mechanism linking Bub1 loss to the p53 pathway.
Gjoerup OV, Wu J, Chandler-Militello D, Williams GL, Zhao J, Schaffhausen B, Jat PS, Roberts TM. Gjoerup OV, et al. Proc Natl Acad Sci U S A. 2007 May 15;104(20):8334-9. doi: 10.1073/pnas.0703164104. Epub 2007 May 8. Proc Natl Acad Sci U S A. 2007. PMID: 17488820 Free PMC article.
Integrative genomic approaches identify IKBKE as a breast cancer oncogene.
Boehm JS, Zhao JJ, Yao J, Kim SY, Firestein R, Dunn IF, Sjostrom SK, Garraway LA, Weremowicz S, Richardson AL, Greulich H, Stewart CJ, Mulvey LA, Shen RR, Ambrogio L, Hirozane-Kishikawa T, Hill DE, Vidal M, Meyerson M, Grenier JK, Hinkle G, Root DE, Roberts TM, Lander ES, Polyak K, Hahn WC. Boehm JS, et al. Among authors: zhao jj. Cell. 2007 Jun 15;129(6):1065-79. doi: 10.1016/j.cell.2007.03.052. Cell. 2007. PMID: 17574021 Free article.
Targeting the phosphoinositide 3-kinase pathway in cancer.
Liu P, Cheng H, Roberts TM, Zhao JJ. Liu P, et al. Among authors: zhao jj. Nat Rev Drug Discov. 2009 Aug;8(8):627-44. doi: 10.1038/nrd2926. Nat Rev Drug Discov. 2009. PMID: 19644473 Free PMC article. Review.
1,005 results