McKinnon PJ - Search Results

1

The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1.

Lee Y, Katyal S, Li Y, El-Khamisy SF, Russell HR, Caldecott KW, McKinnon PJ. Lee Y, et al. Among authors: mckinnon pj. Nat Neurosci. 2009 Aug;12(8):973-80. doi: 10.1038/nn.2375. Epub 2009 Jul 26. Nat Neurosci. 2009. PMID: 19633665 Free PMC article.

2

Disconnecting XRCC1 and DNA ligase III.

Katyal S, McKinnon PJ. Katyal S, et al. Among authors: mckinnon pj. Cell Cycle. 2011 Jul 15;10(14):2269-75. doi: 10.4161/cc.10.14.16495. Epub 2011 Jul 15. Cell Cycle. 2011. PMID: 21636980 Free PMC article.

3

Neurogenesis requires TopBP1 to prevent catastrophic replicative DNA damage in early progenitors.

Lee Y, Katyal S, Downing SM, Zhao J, Russell HR, McKinnon PJ. Lee Y, et al. Among authors: mckinnon pj. Nat Neurosci. 2012 Jun;15(6):819-26. doi: 10.1038/nn.3097. Nat Neurosci. 2012. PMID: 22522401 Free PMC article.

4

Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes.

Katyal S, Lee Y, Nitiss KC, Downing SM, Li Y, Shimada M, Zhao J, Russell HR, Petrini JH, Nitiss JL, McKinnon PJ. Katyal S, et al. Among authors: mckinnon pj. Nat Neurosci. 2014 Jun;17(6):813-21. doi: 10.1038/nn.3715. Epub 2014 May 4. Nat Neurosci. 2014. PMID: 24793032 Free PMC article.

5

XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia.

Hoch NC, Hanzlikova H, Rulten SL, Tétreault M, Komulainen E, Ju L, Hornyak P, Zeng Z, Gittens W, Rey SA, Staras K, Mancini GM, McKinnon PJ, Wang ZQ, Wagner JD; Care4Rare Canada Consortium; Yoon G, Caldecott KW. Hoch NC, et al. Among authors: mckinnon pj. Nature. 2017 Jan 5;541(7635):87-91. doi: 10.1038/nature20790. Epub 2016 Dec 21. Nature. 2017. PMID: 28002403 Free PMC article.

6

DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis.

Enriquez-Rios V, Dumitrache LC, Downing SM, Li Y, Brown EJ, Russell HR, McKinnon PJ. Enriquez-Rios V, et al. Among authors: mckinnon pj. J Neurosci. 2017 Jan 25;37(4):893-905. doi: 10.1523/JNEUROSCI.4213-15.2016. J Neurosci. 2017. PMID: 28123024 Free PMC article.

7

DNA repair deficiency and neurodegeneration.

Katyal S, McKinnon PJ. Katyal S, et al. Among authors: mckinnon pj. Cell Cycle. 2007 Oct 1;6(19):2360-5. doi: 10.4161/cc.6.19.4757. Epub 2007 Jul 18. Cell Cycle. 2007. PMID: 17700067 Review.

8

TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo.

Katyal S, el-Khamisy SF, Russell HR, Li Y, Ju L, Caldecott KW, McKinnon PJ. Katyal S, et al. Among authors: mckinnon pj. EMBO J. 2007 Nov 14;26(22):4720-31. doi: 10.1038/sj.emboj.7601869. Epub 2007 Oct 4. EMBO J. 2007. PMID: 17914460 Free PMC article.

9

DNA strand breaks, neurodegeneration and aging in the brain.

Katyal S, McKinnon PJ. Katyal S, et al. Among authors: mckinnon pj. Mech Ageing Dev. 2008 Jul-Aug;129(7-8):483-91. doi: 10.1016/j.mad.2008.03.008. Epub 2008 Mar 25. Mech Ageing Dev. 2008. PMID: 18455751 Free PMC article. Review.

10

Differential DNA damage signaling accounts for distinct neural apoptotic responses in ATLD and NBS.

Shull ER, Lee Y, Nakane H, Stracker TH, Zhao J, Russell HR, Petrini JH, McKinnon PJ. Shull ER, et al. Among authors: mckinnon pj. Genes Dev. 2009 Jan 15;23(2):171-80. doi: 10.1101/gad.1746609. Genes Dev. 2009. PMID: 19171781 Free PMC article.

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