Peränen J - Search Results

1

Mesencephalic astrocyte-derived neurotrophic factor is neurorestorative in rat model of Parkinson's disease.

Voutilainen MH, Bäck S, Pörsti E, Toppinen L, Lindgren L, Lindholm P, Peränen J, Saarma M, Tuominen RK. Voutilainen MH, et al. Among authors: peranen j. J Neurosci. 2009 Jul 29;29(30):9651-9. doi: 10.1523/JNEUROSCI.0833-09.2009. J Neurosci. 2009. PMID: 19641128 Free PMC article.

2

Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo.

Lindholm P, Voutilainen MH, Laurén J, Peränen J, Leppänen VM, Andressoo JO, Lindahl M, Janhunen S, Kalkkinen N, Timmusk T, Tuominen RK, Saarma M. Lindholm P, et al. Among authors: peranen j. Nature. 2007 Jul 5;448(7149):73-7. doi: 10.1038/nature05957. Nature. 2007. PMID: 17611540

3

MANF is widely expressed in mammalian tissues and differently regulated after ischemic and epileptic insults in rodent brain.

Lindholm P, Peränen J, Andressoo JO, Kalkkinen N, Kokaia Z, Lindvall O, Timmusk T, Saarma M. Lindholm P, et al. Among authors: peranen j. Mol Cell Neurosci. 2008 Nov;39(3):356-71. doi: 10.1016/j.mcn.2008.07.016. Epub 2008 Jul 30. Mol Cell Neurosci. 2008. PMID: 18718866

4

Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neurons.

Palgi M, Lindström R, Peränen J, Piepponen TP, Saarma M, Heino TI. Palgi M, et al. Among authors: peranen j. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2429-34. doi: 10.1073/pnas.0810996106. Epub 2009 Jan 22. Proc Natl Acad Sci U S A. 2009. PMID: 19164766 Free PMC article.

5

The structure of the conserved neurotrophic factors MANF and CDNF explains why they are bifunctional.

Parkash V, Lindholm P, Peränen J, Kalkkinen N, Oksanen E, Saarma M, Leppänen VM, Goldman A. Parkash V, et al. Among authors: peranen j. Protein Eng Des Sel. 2009 Apr;22(4):233-41. doi: 10.1093/protein/gzn080. Epub 2009 Mar 3. Protein Eng Des Sel. 2009. PMID: 19258449

6

Mesencephalic astrocyte-derived neurotrophic factor reduces ischemic brain injury and promotes behavioral recovery in rats.

Airavaara M, Shen H, Kuo CC, Peränen J, Saarma M, Hoffer B, Wang Y. Airavaara M, et al. Among authors: peranen j. J Comp Neurol. 2009 Jul 1;515(1):116-24. doi: 10.1002/cne.22039. J Comp Neurol. 2009. PMID: 19399876 Free PMC article.

7

1H, 13C and 15N resonance assignments of the human mesencephalic astrocyte-derived neurotrophic factor.

Hellman M, Peränen J, Saarma M, Permi P. Hellman M, et al. Among authors: peranen j. Biomol NMR Assign. 2010 Oct;4(2):215-7. doi: 10.1007/s12104-010-9251-8. Epub 2010 Jul 9. Biomol NMR Assign. 2010. PMID: 20617400

8

Characterization of the intracellular localization, processing, and secretion of two glial cell line-derived neurotrophic factor splice isoforms.

Lonka-Nevalaita L, Lume M, Leppänen S, Jokitalo E, Peränen J, Saarma M. Lonka-Nevalaita L, et al. Among authors: peranen j. J Neurosci. 2010 Aug 25;30(34):11403-13. doi: 10.1523/JNEUROSCI.5888-09.2010. J Neurosci. 2010. PMID: 20739562 Free PMC article.

9

Mesencephalic astrocyte-derived neurotrophic factor (MANF) has a unique mechanism to rescue apoptotic neurons.

Hellman M, Arumäe U, Yu LY, Lindholm P, Peränen J, Saarma M, Permi P. Hellman M, et al. Among authors: peranen j. J Biol Chem. 2011 Jan 28;286(4):2675-80. doi: 10.1074/jbc.M110.146738. Epub 2010 Nov 3. J Biol Chem. 2011. PMID: 21047780 Free PMC article.

10

Chronic infusion of CDNF prevents 6-OHDA-induced deficits in a rat model of Parkinson's disease.

Voutilainen MH, Bäck S, Peränen J, Lindholm P, Raasmaja A, Männistö PT, Saarma M, Tuominen RK. Voutilainen MH, et al. Among authors: peranen j. Exp Neurol. 2011 Mar;228(1):99-108. doi: 10.1016/j.expneurol.2010.12.013. Epub 2010 Dec 24. Exp Neurol. 2011. PMID: 21185834

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