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Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia.
Radtke I, Mullighan CG, Ishii M, Su X, Cheng J, Ma J, Ganti R, Cai Z, Goorha S, Pounds SB, Cao X, Obert C, Armstrong J, Zhang J, Song G, Ribeiro RC, Rubnitz JE, Raimondi SC, Shurtleff SA, Downing JR. Radtke I, et al. Among authors: shurtleff sa. Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12944-9. doi: 10.1073/pnas.0903142106. Epub 2009 Jul 27. Proc Natl Acad Sci U S A. 2009. PMID: 19651601 Free PMC article.
A point mutation at tyrosine-809 in the human colony-stimulating factor 1 receptor impairs mitogenesis without abrogating tyrosine kinase activity, association with phosphatidylinositol 3-kinase, or induction of c-fos and junB genes.
Roussel MF, Shurtleff SA, Downing JR, Sherr CJ. Roussel MF, et al. Among authors: shurtleff sa. Proc Natl Acad Sci U S A. 1990 Sep;87(17):6738-42. doi: 10.1073/pnas.87.17.6738. Proc Natl Acad Sci U S A. 1990. PMID: 2168557 Free PMC article.
119 results