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Page 1
In vitro and in vivo characterization of MDX-1401 for therapy of malignant lymphoma.
Cardarelli PM, Moldovan-Loomis MC, Preston B, Black A, Passmore D, Chen TH, Chen S, Liu J, Kuhne MR, Srinivasan M, Assad A, Witte A, Graziano RF, King DJ. Cardarelli PM, et al. Among authors: king dj. Clin Cancer Res. 2009 May 15;15(10):3376-83. doi: 10.1158/1078-0432.CCR-08-3222. Epub 2009 Apr 28. Clin Cancer Res. 2009. PMID: 19401346
CD10 is a key enzyme involved in the activation of tumor-activated peptide prodrug CPI-0004Na and novel analogues: implications for the design of novel peptide prodrugs for the therapy of CD10+ tumors.
Pan C, Cardarelli PM, Nieder MH, Pickford LB, Gangwar S, King DJ, Yarranton GT, Buckman D, Roscoe W, Zhou F, Salles A, Chen TH, Horgan K, Wang YH, Nguyen T, Bebbington CR. Pan C, et al. Among authors: king dj. Cancer Res. 2003 Sep 1;63(17):5526-31. Cancer Res. 2003. PMID: 14500390
Mammalian cell display for the discovery and optimization of antibody therapeutics.
Bowers PM, Horlick RA, Kehry MR, Neben TY, Tomlinson GL, Altobell L, Zhang X, Macomber JL, Krapf IP, Wu BF, McConnell AD, Chau B, Berkebile AD, Hare E, Verdino P, King DJ. Bowers PM, et al. Among authors: king dj. Methods. 2014 Jan 1;65(1):44-56. doi: 10.1016/j.ymeth.2013.06.010. Epub 2013 Jun 20. Methods. 2014. PMID: 23792919
A general approach to antibody thermostabilization.
McConnell AD, Zhang X, Macomber JL, Chau B, Sheffer JC, Rahmanian S, Hare E, Spasojevic V, Horlick RA, King DJ, Bowers PM. McConnell AD, et al. Among authors: king dj. MAbs. 2014;6(5):1274-82. doi: 10.4161/mabs.29680. MAbs. 2014. PMID: 25517312 Free PMC article.
Coupling mammalian cell surface display with somatic hypermutation for the discovery and maturation of human antibodies.
Bowers PM, Horlick RA, Neben TY, Toobian RM, Tomlinson GL, Dalton JL, Jones HA, Chen A, Altobell L 3rd, Zhang X, Macomber JL, Krapf IP, Wu BF, McConnell A, Chau B, Holland T, Berkebile AD, Neben SS, Boyle WJ, King DJ. Bowers PM, et al. Among authors: king dj. Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20455-60. doi: 10.1073/pnas.1114010108. Epub 2011 Dec 7. Proc Natl Acad Sci U S A. 2011. PMID: 22158898 Free PMC article.
Humanization of antibodies using heavy chain complementarity-determining region 3 grafting coupled with in vitro somatic hypermutation.
Bowers PM, Neben TY, Tomlinson GL, Dalton JL, Altobell L, Zhang X, Macomber JL, Wu BF, Toobian RM, McConnell AD, Verdino P, Chau B, Horlick RA, King DJ. Bowers PM, et al. Among authors: king dj. J Biol Chem. 2013 Mar 15;288(11):7688-7696. doi: 10.1074/jbc.M112.445502. Epub 2013 Jan 25. J Biol Chem. 2013. PMID: 23355464 Free PMC article.
339 results