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Association of colonic and endometrial carcinomas in Portuguese families with hereditary nonpolyposis colorectal carcinoma significantly increases the probability of detecting a pathogenic mutation in mismatch repair genes, primarily the MSH2 gene.
Lage PA, Albuquerque C, Sousa RG, Cravo ML, Salazar M, Francisco I, Maia L, Claro I, Suspiro A, Rodrigues P, Raposo H, Fidalgo PA, Nobre-Leitão C. Lage PA, et al. Among authors: rodrigues p. Cancer. 2004 Jul 1;101(1):172-7. doi: 10.1002/cncr.20320. Cancer. 2004. PMID: 15222003 Free article.
Management of Portuguese patients with hyperplastic polyposis and screening of at-risk first-degree relatives: a contribution for future guidelines based on a clinical study.
Lage P, Cravo M, Sousa R, Chaves P, Salazar M, Fonseca R, Claro I, Suspiro A, Rodrigues P, Raposo H, Fidalgo P, Nobre-Leitão C. Lage P, et al. Among authors: rodrigues p. Am J Gastroenterol. 2004 Sep;99(9):1779-84. doi: 10.1111/j.1572-0241.2004.30178.x. Am J Gastroenterol. 2004. PMID: 15330918
APC or MUTYH mutations account for the majority of clinically well-characterized families with FAP and AFAP phenotype and patients with more than 30 adenomas.
Filipe B, Baltazar C, Albuquerque C, Fragoso S, Lage P, Vitoriano I, Mão de Ferro S, Claro I, Rodrigues P, Fidalgo P, Chaves P, Cravo M, Nobre Leitão C. Filipe B, et al. Among authors: rodrigues p. Clin Genet. 2009 Sep;76(3):242-55. doi: 10.1111/j.1399-0004.2009.01241.x. Clin Genet. 2009. PMID: 19793053
Colorectal cancers show distinct mutation spectra in members of the canonical WNT signaling pathway according to their anatomical location and type of genetic instability.
Albuquerque C, Baltazar C, Filipe B, Penha F, Pereira T, Smits R, Cravo M, Lage P, Fidalgo P, Claro I, Rodrigues P, Veiga I, Ramos JS, Fonseca I, Leitão CN, Fodde R. Albuquerque C, et al. Among authors: rodrigues p. Genes Chromosomes Cancer. 2010 Aug;49(8):746-59. doi: 10.1002/gcc.20786. Genes Chromosomes Cancer. 2010. PMID: 20544848
Familial colorectal cancer type X syndrome: two distinct molecular entities?
Francisco I, Albuquerque C, Lage P, Belo H, Vitoriano I, Filipe B, Claro I, Ferreira S, Rodrigues P, Chaves P, Leitão CN, Pereira AD. Francisco I, et al. Among authors: rodrigues p. Fam Cancer. 2011 Dec;10(4):623-31. doi: 10.1007/s10689-011-9473-7. Fam Cancer. 2011. PMID: 21837511
1,511 results