Bielas JH - Search Results

1

Molecularly evolved thymidylate synthase inhibits 5-fluorodeoxyuridine toxicity in human hematopoietic cells.

Bielas JH, Schmitt MW, Icreverzi A, Ericson NG, Loeb LA. Bielas JH, et al. Hum Gene Ther. 2009 Dec;20(12):1703-7. doi: 10.1089/hum.2009.053. Hum Gene Ther. 2009. PMID: 19694534 Free PMC article.

2

Mutator phenotype in cancer: timing and perspectives.

Bielas JH, Loeb LA. Bielas JH, et al. Environ Mol Mutagen. 2005 Mar-Apr;45(2-3):206-13. doi: 10.1002/em.20111. Environ Mol Mutagen. 2005. PMID: 15672382 Review.

3

Quantification of random genomic mutations.

Bielas JH, Loeb LA. Bielas JH, et al. Nat Methods. 2005 Apr;2(4):285-90. doi: 10.1038/nmeth751. Epub 2005 Mar 23. Nat Methods. 2005. PMID: 15782221

4

Generation of mutator mutants during carcinogenesis.

Venkatesan RN, Bielas JH, Loeb LA. Venkatesan RN, et al. Among authors: bielas jh. DNA Repair (Amst). 2006 Mar 7;5(3):294-302. doi: 10.1016/j.dnarep.2005.10.012. Epub 2005 Dec 15. DNA Repair (Amst). 2006. PMID: 16359931 Review.

5

Human cancers express a mutator phenotype.

Bielas JH, Loeb KR, Rubin BP, True LD, Loeb LA. Bielas JH, et al. Proc Natl Acad Sci U S A. 2006 Nov 28;103(48):18238-42. doi: 10.1073/pnas.0607057103. Epub 2006 Nov 15. Proc Natl Acad Sci U S A. 2006. PMID: 17108085 Free PMC article.

6

Limits to the Human Cancer Genome Project?

Loeb LA, Bielas JH. Loeb LA, et al. Among authors: bielas jh. Science. 2007 Feb 9;315(5813):762; author reply 764-5. Science. 2007. PMID: 17297724 No abstract available.

7

LOH-proficient embryonic stem cells: a model of cancer progenitor cells?

Bielas JH, Venkatesan RN, Loeb LA. Bielas JH, et al. Trends Genet. 2007 Apr;23(4):154-7. doi: 10.1016/j.tig.2007.02.009. Epub 2007 Feb 27. Trends Genet. 2007. PMID: 17328987 Review.

8

Mitochondrial point mutations do not limit the natural lifespan of mice.

Vermulst M, Bielas JH, Kujoth GC, Ladiges WC, Rabinovitch PS, Prolla TA, Loeb LA. Vermulst M, et al. Among authors: bielas jh. Nat Genet. 2007 Apr;39(4):540-3. doi: 10.1038/ng1988. Epub 2007 Mar 4. Nat Genet. 2007. PMID: 17334366

9

DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice.

Vermulst M, Wanagat J, Kujoth GC, Bielas JH, Rabinovitch PS, Prolla TA, Loeb LA. Vermulst M, et al. Among authors: bielas jh. Nat Genet. 2008 Apr;40(4):392-4. doi: 10.1038/ng.95. Epub 2008 Mar 2. Nat Genet. 2008. PMID: 18311139

10

Cancers exhibit a mutator phenotype: clinical implications.

Loeb LA, Bielas JH, Beckman RA. Loeb LA, et al. Among authors: bielas jh. Cancer Res. 2008 May 15;68(10):3551-7; discussion 3557. doi: 10.1158/0008-5472.CAN-07-5835. Cancer Res. 2008. PMID: 18483233 Review.

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