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Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons.
Goldberg MS, Fleming SM, Palacino JJ, Cepeda C, Lam HA, Bhatnagar A, Meloni EG, Wu N, Ackerson LC, Klapstein GJ, Gajendiran M, Roth BL, Chesselet MF, Maidment NT, Levine MS, Shen J. Goldberg MS, et al. Among authors: shen j. J Biol Chem. 2003 Oct 31;278(44):43628-35. doi: 10.1074/jbc.M308947200. Epub 2003 Aug 20. J Biol Chem. 2003. PMID: 12930822 Free article.
Mitochondrial dysfunction and oxidative damage in parkin-deficient mice.
Palacino JJ, Sagi D, Goldberg MS, Krauss S, Motz C, Wacker M, Klose J, Shen J. Palacino JJ, et al. Among authors: shen j. J Biol Chem. 2004 Apr 30;279(18):18614-22. doi: 10.1074/jbc.M401135200. Epub 2004 Feb 24. J Biol Chem. 2004. PMID: 14985362 Free article.
LRRK2 regulates synaptic vesicle endocytosis.
Shin N, Jeong H, Kwon J, Heo HY, Kwon JJ, Yun HJ, Kim CH, Han BS, Tong Y, Shen J, Hatano T, Hattori N, Kim KS, Chang S, Seol W. Shin N, et al. Among authors: shen j. Exp Cell Res. 2008 Jun 10;314(10):2055-65. doi: 10.1016/j.yexcr.2008.02.015. Epub 2008 Mar 5. Exp Cell Res. 2008. PMID: 18445495
Enhanced sensitivity to group II mGlu receptor activation at corticostriatal synapses in mice lacking the familial parkinsonism-linked genes PINK1 or Parkin.
Martella G, Platania P, Vita D, Sciamanna G, Cuomo D, Tassone A, Tscherter A, Kitada T, Bonsi P, Shen J, Pisani A. Martella G, et al. Among authors: shen j. Exp Neurol. 2009 Feb;215(2):388-96. doi: 10.1016/j.expneurol.2008.11.001. Epub 2008 Nov 21. Exp Neurol. 2009. PMID: 19071114 Free PMC article.
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