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Notch3 Arg170Cys knock-in mice display pathologic and clinical features of the neurovascular disorder cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.
Wallays G, Nuyens D, Silasi-Mansat R, Souffreau J, Callaerts-Vegh Z, Van Nuffelen A, Moons L, D'Hooge R, Lupu F, Carmeliet P, Collen D, Dewerchin M. Wallays G, et al. Among authors: van nuffelen a. Arterioscler Thromb Vasc Biol. 2011 Dec;31(12):2881-8. doi: 10.1161/ATVBAHA.111.237859. Epub 2011 Sep 22. Arterioscler Thromb Vasc Biol. 2011. PMID: 21940951