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Page 1
Glycosphingolipids and insulin resistance.
Aerts JM, Boot RG, van Eijk M, Groener J, Bijl N, Lombardo E, Bietrix FM, Dekker N, Groen AK, Ottenhoff R, van Roomen C, Aten J, Serlie M, Langeveld M, Wennekes T, Overkleeft HS. Aerts JM, et al. Among authors: aten j. Adv Exp Med Biol. 2011;721:99-119. doi: 10.1007/978-1-4614-0650-1_7. Adv Exp Med Biol. 2011. PMID: 21910085 Review.
Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity.
Aerts JM, Ottenhoff R, Powlson AS, Grefhorst A, van Eijk M, Dubbelhuis PF, Aten J, Kuipers F, Serlie MJ, Wennekes T, Sethi JK, O'Rahilly S, Overkleeft HS. Aerts JM, et al. Among authors: aten j. Diabetes. 2007 May;56(5):1341-9. doi: 10.2337/db06-1619. Epub 2007 Feb 7. Diabetes. 2007. PMID: 17287460 Free PMC article.
Reducing glycosphingolipid content in adipose tissue of obese mice restores insulin sensitivity, adipogenesis and reduces inflammation.
van Eijk M, Aten J, Bijl N, Ottenhoff R, van Roomen CP, Dubbelhuis PF, Seeman I, Ghauharali-van der Vlugt K, Overkleeft HS, Arbeeny C, Groen AK, Aerts JM. van Eijk M, et al. Among authors: aten j. PLoS One. 2009;4(3):e4723. doi: 10.1371/journal.pone.0004723. Epub 2009 Mar 23. PLoS One. 2009. PMID: 19305508 Free PMC article.
Fasting reduces liver fibrosis in a mouse model for chronic cholangiopathies.
Sokolović A, van Roomen CP, Ottenhoff R, Scheij S, Hiralall JK, Claessen N, Aten J, Oude Elferink RP, Groen AK, Sokolović M. Sokolović A, et al. Among authors: aten j. Biochim Biophys Acta. 2013 Oct;1832(10):1482-91. doi: 10.1016/j.bbadis.2013.05.012. Epub 2013 May 22. Biochim Biophys Acta. 2013. PMID: 23707514 Free article.
Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice.
Marques AR, Aten J, Ottenhoff R, van Roomen CP, Herrera Moro D, Claessen N, Vinueza Veloz MF, Zhou K, Lin Z, Mirzaian M, Boot RG, De Zeeuw CI, Overkleeft HS, Yildiz Y, Aerts JM. Marques AR, et al. Among authors: aten j. PLoS One. 2015 Aug 14;10(8):e0135889. doi: 10.1371/journal.pone.0135889. eCollection 2015. PLoS One. 2015. PMID: 26275242 Free PMC article.
Novel activity-based probes for broad-spectrum profiling of retaining β-exoglucosidases in situ and in vivo.
Kallemeijn WW, Li KY, Witte MD, Marques AR, Aten J, Scheij S, Jiang J, Willems LI, Voorn-Brouwer TM, van Roomen CP, Ottenhoff R, Boot RG, van den Elst H, Walvoort MT, Florea BI, Codée JD, van der Marel GA, Aerts JM, Overkleeft HS. Kallemeijn WW, et al. Among authors: aten j. Angew Chem Int Ed Engl. 2012 Dec 7;51(50):12529-33. doi: 10.1002/anie.201207771. Epub 2012 Nov 8. Angew Chem Int Ed Engl. 2012. PMID: 23139194
218 results