Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome.
Habashi JP, Judge DP, Holm TM, Cohn RD, Loeys BL, Cooper TK, Myers L, Klein EC, Liu G, Calvi C, Podowski M, Neptune ER, Halushka MK, Bedja D, Gabrielson K, Rifkin DB, Carta L, Ramirez F, Huso DL, Dietz HC.
Habashi JP, et al. Among authors: bedja d.
Science. 2006 Apr 7;312(5770):117-21. doi: 10.1126/science.1124287.
Science. 2006.
PMID: 16601194
Free PMC article.