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Dynamic and accurate assessment of acetaminophen-induced hepatotoxicity by integrated photoacoustic imaging and mechanistic biomarkers in vivo.
Brillant N, Elmasry M, Burton NC, Rodriguez JM, Sharkey JW, Fenwick S, Poptani H, Kitteringham NR, Goldring CE, Kipar A, Park BK, Antoine DJ. Brillant N, et al. Among authors: kipar a. Toxicol Appl Pharmacol. 2017 Oct 1;332:64-74. doi: 10.1016/j.taap.2017.07.019. Epub 2017 Jul 26. Toxicol Appl Pharmacol. 2017. PMID: 28755860 Free article.
Diet restriction inhibits apoptosis and HMGB1 oxidation and promotes inflammatory cell recruitment during acetaminophen hepatotoxicity.
Antoine DJ, Williams DP, Kipar A, Laverty H, Park BK. Antoine DJ, et al. Among authors: kipar a. Mol Med. 2010 Nov-Dec;16(11-12):479-90. doi: 10.2119/molmed.2010.00126. Epub 2010 Aug 27. Mol Med. 2010. Retraction in: Mol Med. 2020 Dec 30;26(1):130. doi: 10.1186/s10020-020-00262-3 PMID: 20811657 Free PMC article. Retracted.
A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug-induced liver injury and postinjury inflammation in mice.
Lundbäck P, Lea JD, Sowinska A, Ottosson L, Fürst CM, Steen J, Aulin C, Clarke JI, Kipar A, Klevenvall L, Yang H, Palmblad K, Park BK, Tracey KJ, Blom AM, Andersson U, Antoine DJ, Erlandsson Harris H. Lundbäck P, et al. Among authors: kipar a. Hepatology. 2016 Nov;64(5):1699-1710. doi: 10.1002/hep.28736. Epub 2016 Sep 1. Hepatology. 2016. PMID: 27474782 Free PMC article.
Circulating levels of miR-122 increase post-mortem, particularly following lethal dosing with pentobarbital sodium: implications for pre-clinical liver injury studies.
Clarke JI, Forootan SS, Lea JD, Howell LS, Rodriguez JM, Kipar A, Goldring CE, Park BK, Copple IM, Antoine DJ. Clarke JI, et al. Among authors: kipar a. Toxicol Res (Camb). 2017 Apr 11;6(4):406-411. doi: 10.1039/c6tx00442c. eCollection 2017 Jul 1. Toxicol Res (Camb). 2017. PMID: 30090508 Free PMC article.
Exploring the translational disconnect between the murine and human inflammatory response: analysis of LPS dose-response relationship in murine versus human cell lines and implications for translation into murine models of sepsis.
McCarron EP, Williams DP, Antoine DJ, Kipar A, Lemm J, Stehr S, Welters ID. McCarron EP, et al. Among authors: kipar a. J Inflamm Res. 2015 Oct 16;8:201-9. doi: 10.2147/JIR.S89097. eCollection 2015. J Inflamm Res. 2015. PMID: 26527892 Free PMC article.
219 results