Irwin MS - Search Results

1

Chemotherapy induces NEDP1-mediated destabilization of MDM2.

Watson IR, Li BK, Roche O, Blanch A, Ohh M, Irwin MS. Watson IR, et al. Among authors: irwin ms. Oncogene. 2010 Jan 14;29(2):297-304. doi: 10.1038/onc.2009.314. Epub 2009 Sep 28. Oncogene. 2010. PMID: 19784069

2

Expression of p53 in renal carcinoma cells is independent of pVHL.

Stickle NH, Cheng LS, Watson IR, Alon N, Malkin D, Irwin MS, Ohh M. Stickle NH, et al. Among authors: irwin ms. Mutat Res. 2005 Oct 15;578(1-2):23-32. doi: 10.1016/j.mrfmmm.2005.02.016. Epub 2005 Jul 5. Mutat Res. 2005. PMID: 15998523

3

Ubiquitin and ubiquitin-like modifications of the p53 family.

Watson IR, Irwin MS. Watson IR, et al. Among authors: irwin ms. Neoplasia. 2006 Aug;8(8):655-66. doi: 10.1593/neo.06439. Neoplasia. 2006. PMID: 16925948 Free PMC article. Review.

4

Mdm2-mediated NEDD8 modification of TAp73 regulates its transactivation function.

Watson IR, Blanch A, Lin DC, Ohh M, Irwin MS. Watson IR, et al. Among authors: irwin ms. J Biol Chem. 2006 Nov 10;281(45):34096-103. doi: 10.1074/jbc.M603654200. Epub 2006 Sep 14. J Biol Chem. 2006. PMID: 16980297 Free article.

5

Cyclooxygenase inhibitors modulate the p53/HDM2 pathway and enhance chemotherapy-induced apoptosis in neuroblastoma.

Lau L, Hansford LM, Cheng LS, Hang M, Baruchel S, Kaplan DR, Irwin MS. Lau L, et al. Among authors: irwin ms. Oncogene. 2007 Mar 22;26(13):1920-31. doi: 10.1038/sj.onc.1209981. Epub 2006 Sep 18. Oncogene. 2007. PMID: 16983334

6

VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail.

Evans AJ, Russell RC, Roche O, Burry TN, Fish JE, Chow VW, Kim WY, Saravanan A, Maynard MA, Gervais ML, Sufan RI, Roberts AM, Wilson LA, Betten M, Vandewalle C, Berx G, Marsden PA, Irwin MS, Teh BT, Jewett MA, Ohh M. Evans AJ, et al. Among authors: irwin ms. Mol Cell Biol. 2007 Jan;27(1):157-69. doi: 10.1128/MCB.00892-06. Epub 2006 Oct 23. Mol Cell Biol. 2007. PMID: 17060462 Free PMC article.

7

HDM2 antagonist Nutlin-3 disrupts p73-HDM2 binding and enhances p73 function.

Lau LM, Nugent JK, Zhao X, Irwin MS. Lau LM, et al. Among authors: irwin ms. Oncogene. 2008 Feb 7;27(7):997-1003. doi: 10.1038/sj.onc.1210707. Epub 2007 Aug 13. Oncogene. 2008. PMID: 17700533

8

Regulation of endocytosis via the oxygen-sensing pathway.

Wang Y, Roche O, Yan MS, Finak G, Evans AJ, Metcalf JL, Hast BE, Hanna SC, Wondergem B, Furge KA, Irwin MS, Kim WY, Teh BT, Grinstein S, Park M, Marsden PA, Ohh M. Wang Y, et al. Among authors: irwin ms. Nat Med. 2009 Mar;15(3):319-24. doi: 10.1038/nm.1922. Epub 2009 Mar 1. Nat Med. 2009. PMID: 19252501

9

Cyclooxygenase inhibitors differentially modulate p73 isoforms in neuroblastoma.

Lau LM, Wolter JK, Lau JT, Cheng LS, Smith KM, Hansford LM, Zhang L, Baruchel S, Robinson F, Irwin MS. Lau LM, et al. Among authors: irwin ms. Oncogene. 2009 May 14;28(19):2024-33. doi: 10.1038/onc.2009.59. Epub 2009 Apr 13. Oncogene. 2009. PMID: 19363520

10

Suppression of hypoxia-inducible factor 2alpha restores p53 activity via Hdm2 and reverses chemoresistance of renal carcinoma cells.

Roberts AM, Watson IR, Evans AJ, Foster DA, Irwin MS, Ohh M. Roberts AM, et al. Among authors: irwin ms. Cancer Res. 2009 Dec 1;69(23):9056-64. doi: 10.1158/0008-5472.CAN-09-1770. Epub 2009 Nov 17. Cancer Res. 2009. PMID: 19920202 Free PMC article.

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