Curtin NJ - Search Results

1

Vasoactivity of AG014699, a clinically active small molecule inhibitor of poly(ADP-ribose) polymerase: a contributory factor to chemopotentiation in vivo?

Ali M, Telfer BA, McCrudden C, O'Rourke M, Thomas HD, Kamjoo M, Kyle S, Robson T, Shaw C, Hirst DG, Curtin NJ, Williams KJ. Ali M, et al. Among authors: curtin nj. Clin Cancer Res. 2009 Oct 1;15(19):6106-12. doi: 10.1158/1078-0432.CCR-09-0398. Epub 2009 Sep 29. Clin Cancer Res. 2009. PMID: 19789326 Free PMC article.

2

Dipyridamole potentiates antipurine antifolate activity in the presence of hypoxanthine in tumor cells but not in normal tissues in vitro.

Marshman E, Newell DR, Calvert AH, Dickinson AM, Patel HR, Campbell FC, Curtin NJ. Marshman E, et al. Among authors: curtin nj. Clin Cancer Res. 1998 Nov;4(11):2895-902. Clin Cancer Res. 1998. PMID: 9829758

3

Cellular ATP depletion by LY309887 as a predictor of growth inhibition in human tumor cell lines.

Lu X, Errington J, Chen VJ, Curtin NJ, Boddy AV, Newell DR. Lu X, et al. Among authors: curtin nj. Clin Cancer Res. 2000 Jan;6(1):271-7. Clin Cancer Res. 2000. PMID: 10656458

4

Potentiation of temozolomide and topotecan growth inhibition and cytotoxicity by novel poly(adenosine diphosphoribose) polymerase inhibitors in a panel of human tumor cell lines.

Delaney CA, Wang LZ, Kyle S, White AW, Calvert AH, Curtin NJ, Durkacz BW, Hostomsky Z, Newell DR. Delaney CA, et al. Among authors: curtin nj. Clin Cancer Res. 2000 Jul;6(7):2860-7. Clin Cancer Res. 2000. PMID: 10914735

5

In vitro and in vivo properties of novel nucleoside transport inhibitors with improved pharmacological properties that potentiate antifolate activity.

Smith PG, Thomas HD, Barlow HC, Griffin RJ, Golding BT, Calvert AH, Newell DR, Curtin NJ. Smith PG, et al. Among authors: curtin nj. Clin Cancer Res. 2001 Jul;7(7):2105-13. Clin Cancer Res. 2001. PMID: 11448930

6

Novel tricyclic poly(ADP-ribose) polymerase-1 inhibitors with potent anticancer chemopotentiating activity: design, synthesis, and X-ray cocrystal structure.

Canan Koch SS, Thoresen LH, Tikhe JG, Maegley KA, Almassy RJ, Li J, Yu XH, Zook SE, Kumpf RA, Zhang C, Boritzki TJ, Mansour RN, Zhang KE, Ekker A, Calabrese CR, Curtin NJ, Kyle S, Thomas HD, Wang LZ, Calvert AH, Golding BT, Griffin RJ, Newell DR, Webber SE, Hostomsky Z. Canan Koch SS, et al. Among authors: curtin nj. J Med Chem. 2002 Nov 7;45(23):4961-74. doi: 10.1021/jm020259n. J Med Chem. 2002. PMID: 12408707

7

Identification of potent nontoxic poly(ADP-Ribose) polymerase-1 inhibitors: chemopotentiation and pharmacological studies.

Calabrese CR, Batey MA, Thomas HD, Durkacz BW, Wang LZ, Kyle S, Skalitzky D, Li J, Zhang C, Boritzki T, Maegley K, Calvert AH, Hostomsky Z, Newell DR, Curtin NJ. Calabrese CR, et al. Among authors: curtin nj. Clin Cancer Res. 2003 Jul;9(7):2711-8. Clin Cancer Res. 2003. PMID: 12855651

8

Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1.

Veuger SJ, Curtin NJ, Richardson CJ, Smith GC, Durkacz BW. Veuger SJ, et al. Among authors: curtin nj. Cancer Res. 2003 Sep 15;63(18):6008-15. Cancer Res. 2003. PMID: 14522929

9

Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361.

Calabrese CR, Almassy R, Barton S, Batey MA, Calvert AH, Canan-Koch S, Durkacz BW, Hostomsky Z, Kumpf RA, Kyle S, Li J, Maegley K, Newell DR, Notarianni E, Stratford IJ, Skalitzky D, Thomas HD, Wang LZ, Webber SE, Williams KJ, Curtin NJ. Calabrese CR, et al. Among authors: curtin nj. J Natl Cancer Inst. 2004 Jan 7;96(1):56-67. doi: 10.1093/jnci/djh005. J Natl Cancer Inst. 2004. PMID: 14709739

10

Novel poly(ADP-ribose) polymerase-1 inhibitor, AG14361, restores sensitivity to temozolomide in mismatch repair-deficient cells.

Curtin NJ, Wang LZ, Yiakouvaki A, Kyle S, Arris CA, Canan-Koch S, Webber SE, Durkacz BW, Calvert HA, Hostomsky Z, Newell DR. Curtin NJ, et al. Clin Cancer Res. 2004 Feb 1;10(3):881-9. doi: 10.1158/1078-0432.ccr-1144-3. Clin Cancer Res. 2004. PMID: 14871963

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