Nukina N - Search Results

1

RNAi screening in Drosophila cells identifies new modifiers of mutant huntingtin aggregation.

Doumanis J, Wada K, Kino Y, Moore AW, Nukina N. Doumanis J, et al. Among authors: nukina n. PLoS One. 2009 Sep 30;4(9):e7275. doi: 10.1371/journal.pone.0007275. PLoS One. 2009. PMID: 19789644 Free PMC article.

2

Large-scale RNA interference screening in mammalian cells identifies novel regulators of mutant huntingtin aggregation.

Yamanaka T, Wong HK, Tosaki A, Bauer PO, Wada K, Kurosawa M, Shimogori T, Hattori N, Nukina N. Yamanaka T, et al. Among authors: nukina n. PLoS One. 2014 Apr 4;9(4):e93891. doi: 10.1371/journal.pone.0093891. eCollection 2014. PLoS One. 2014. PMID: 24705917 Free PMC article.

3

Inhibition of Rho kinases enhances the degradation of mutant huntingtin.

Bauer PO, Wong HK, Oyama F, Goswami A, Okuno M, Kino Y, Miyazaki H, Nukina N. Bauer PO, et al. Among authors: nukina n. J Biol Chem. 2009 May 8;284(19):13153-64. doi: 10.1074/jbc.M809229200. Epub 2009 Mar 11. J Biol Chem. 2009. PMID: 19278999 Free PMC article.

4

Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein.

Bauer PO, Goswami A, Wong HK, Okuno M, Kurosawa M, Yamada M, Miyazaki H, Matsumoto G, Kino Y, Nagai Y, Nukina N. Bauer PO, et al. Among authors: nukina n. Nat Biotechnol. 2010 Mar;28(3):256-63. doi: 10.1038/nbt.1608. Epub 2010 Feb 28. Nat Biotechnol. 2010. PMID: 20190739

5

Selection of behaviors and segmental coordination during larval locomotion is disrupted by nuclear polyglutamine inclusions in a new Drosophila Huntington's disease-like model.

Nishimura Y, Yalgin C, Akimoto S, Doumanis J, Sasajima R, Nukina N, Miyakawa H, Moore AW, Morimoto T. Nishimura Y, et al. Among authors: nukina n. J Neurogenet. 2010 Dec;24(4):194-206. doi: 10.3109/01677063.2010.514367. J Neurogenet. 2010. PMID: 21087194

6

FUS/TLS acts as an aggregation-dependent modifier of polyglutamine disease model mice.

Kino Y, Washizu C, Kurosawa M, Yamada M, Doi H, Takumi T, Adachi H, Katsuno M, Sobue G, Hicks GG, Hattori N, Shimogori T, Nukina N. Kino Y, et al. Among authors: nukina n. Sci Rep. 2016 Oct 14;6:35236. doi: 10.1038/srep35236. Sci Rep. 2016. PMID: 27739513 Free PMC article.

7

Intracellular localization and splicing regulation of FUS/TLS are variably affected by amyotrophic lateral sclerosis-linked mutations.

Kino Y, Washizu C, Aquilanti E, Okuno M, Kurosawa M, Yamada M, Doi H, Nukina N. Kino Y, et al. Among authors: nukina n. Nucleic Acids Res. 2011 Apr;39(7):2781-98. doi: 10.1093/nar/gkq1162. Epub 2010 Nov 24. Nucleic Acids Res. 2011. PMID: 21109527 Free PMC article.

8

Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins.

Matsumoto G, Wada K, Okuno M, Kurosawa M, Nukina N. Matsumoto G, et al. Among authors: nukina n. Mol Cell. 2011 Oct 21;44(2):279-89. doi: 10.1016/j.molcel.2011.07.039. Mol Cell. 2011. PMID: 22017874 Free article.

9

FACS-array-based cell purification yields a specific transcriptome of striatal medium spiny neurons in a murine Huntington disease model.

Miyazaki H, Yamanaka T, Oyama F, Kino Y, Kurosawa M, Yamada-Kurosawa M, Yamano R, Shimogori T, Hattori N, Nukina N. Miyazaki H, et al. Among authors: nukina n. J Biol Chem. 2020 Jul 17;295(29):9768-9785. doi: 10.1074/jbc.RA120.012983. Epub 2020 Jun 4. J Biol Chem. 2020. PMID: 32499373 Free PMC article.

10

Depletion of p62 reduces nuclear inclusions and paradoxically ameliorates disease phenotypes in Huntington's model mice.

Kurosawa M, Matsumoto G, Kino Y, Okuno M, Kurosawa-Yamada M, Washizu C, Taniguchi H, Nakaso K, Yanagawa T, Warabi E, Shimogori T, Sakurai T, Hattori N, Nukina N. Kurosawa M, et al. Among authors: nukina n. Hum Mol Genet. 2015 Feb 15;24(4):1092-105. doi: 10.1093/hmg/ddu522. Epub 2014 Oct 9. Hum Mol Genet. 2015. PMID: 25305080

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