Brown BD - Search Results

1

In vivo delivery of a microRNA-regulated transgene induces antigen-specific regulatory T cells and promotes immunologic tolerance.

Annoni A, Brown BD, Cantore A, Sergi LS, Naldini L, Roncarolo MG. Annoni A, et al. Among authors: brown bd. Blood. 2009 Dec 10;114(25):5152-61. doi: 10.1182/blood-2009-04-214569. Blood. 2009. PMID: 19794140 Free PMC article.

2

Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer.

Brown BD, Venneri MA, Zingale A, Sergi Sergi L, Naldini L. Brown BD, et al. Nat Med. 2006 May;12(5):585-91. doi: 10.1038/nm1398. Epub 2006 Apr 23. Nat Med. 2006. PMID: 16633348

3

In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance.

Brown BD, Sitia G, Annoni A, Hauben E, Sergi LS, Zingale A, Roncarolo MG, Guidotti LG, Naldini L. Brown BD, et al. Blood. 2007 Apr 1;109(7):2797-805. doi: 10.1182/blood-2006-10-049312. Blood. 2007. PMID: 17170119 Free article.

4

A microRNA-regulated lentiviral vector mediates stable correction of hemophilia B mice.

Brown BD, Cantore A, Annoni A, Sergi LS, Lombardo A, Della Valle P, D'Angelo A, Naldini L. Brown BD, et al. Blood. 2007 Dec 15;110(13):4144-52. doi: 10.1182/blood-2007-03-078493. Epub 2007 Aug 28. Blood. 2007. PMID: 17726165 Free article.

5

Endogenous microRNA can be broadly exploited to regulate transgene expression according to tissue, lineage and differentiation state.

Brown BD, Gentner B, Cantore A, Colleoni S, Amendola M, Zingale A, Baccarini A, Lazzari G, Galli C, Naldini L. Brown BD, et al. Nat Biotechnol. 2007 Dec;25(12):1457-67. doi: 10.1038/nbt1372. Epub 2007 Nov 16. Nat Biotechnol. 2007. PMID: 18026085

6

Stable knockdown of microRNA in vivo by lentiviral vectors.

Gentner B, Schira G, Giustacchini A, Amendola M, Brown BD, Ponzoni M, Naldini L. Gentner B, et al. Among authors: brown bd. Nat Methods. 2009 Jan;6(1):63-6. doi: 10.1038/nmeth.1277. Epub 2008 Nov 30. Nat Methods. 2009. PMID: 19043411

7

Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications.

Brown BD, Naldini L. Brown BD, et al. Nat Rev Genet. 2009 Aug;10(8):578-85. doi: 10.1038/nrg2628. Nat Rev Genet. 2009. PMID: 19609263 Review.

8

HIV-1-derived lentiviral vectors directly activate plasmacytoid dendritic cells, which in turn induce the maturation of myeloid dendritic cells.

Rossetti M, Gregori S, Hauben E, Brown BD, Sergi LS, Naldini L, Roncarolo MG. Rossetti M, et al. Among authors: brown bd. Hum Gene Ther. 2011 Feb;22(2):177-88. doi: 10.1089/hum.2010.085. Epub 2011 Jan 14. Hum Gene Ther. 2011. PMID: 20825284

9

Stealth gene therapy.

Brown BD. Brown BD. Blood. 2013 Mar 21;121(12):2168-9. doi: 10.1182/blood-2013-01-480368. Blood. 2013. PMID: 23520327 Free article. No abstract available.

10

Immune tolerance promotion by LSEC-specific lentiviral vector-mediated expression of the transgene regulated by the stabilin-2 promoter.

Borroni E, Borsotti C, Cirsmaru RA, Kalandadze V, Famà R, Merlin S, Brown B, Follenzi A. Borroni E, et al. Mol Ther Nucleic Acids. 2024 Jan 17;35(1):102116. doi: 10.1016/j.omtn.2024.102116. eCollection 2024 Mar 12. Mol Ther Nucleic Acids. 2024. PMID: 38333675 Free PMC article.

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