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Page 1
Discovery and development of a potent and highly selective small molecule muscarinic acetylcholine receptor subtype I (mAChR 1 or M1) antagonist in vitro and in vivo probe.
Weaver CD, Sheffler DJ, Lewis LM, Bridges TM, Williams R, Nalywajko NT, Kennedy JP, Mulder MM, Jadhav S, Aldrich LA, Jones CK, Marlo JE, Niswender CM, Mock MM, Zheng F, Conn PJ, Lindsley CW. Weaver CD, et al. Among authors: niswender cm. Curr Top Med Chem. 2009;9(13):1217-26. doi: 10.2174/156802609789753635. Curr Top Med Chem. 2009. PMID: 19807667 Free PMC article. Review.
mGluR7's lucky number.
Conn PJ, Niswender CM. Conn PJ, et al. Among authors: niswender cm. Proc Natl Acad Sci U S A. 2006 Jan 10;103(2):251-2. doi: 10.1073/pnas.0510051103. Epub 2006 Jan 3. Proc Natl Acad Sci U S A. 2006. PMID: 16407154 Free PMC article. No abstract available.
An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission.
Shirey JK, Xiang Z, Orton D, Brady AE, Johnson KA, Williams R, Ayala JE, Rodriguez AL, Wess J, Weaver D, Niswender CM, Conn PJ. Shirey JK, et al. Among authors: niswender cm. Nat Chem Biol. 2008 Jan;4(1):42-50. doi: 10.1038/nchembio.2007.55. Epub 2007 Dec 2. Nat Chem Biol. 2008. PMID: 18059262
Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4.
Niswender CM, Johnson KA, Weaver CD, Jones CK, Xiang Z, Luo Q, Rodriguez AL, Marlo JE, de Paulis T, Thompson AD, Days EL, Nalywajko T, Austin CA, Williams MB, Ayala JE, Williams R, Lindsley CW, Conn PJ. Niswender CM, et al. Mol Pharmacol. 2008 Nov;74(5):1345-58. doi: 10.1124/mol.108.049551. Epub 2008 Jul 29. Mol Pharmacol. 2008. PMID: 18664603 Free PMC article.
269 results