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Functional interchangeability of rod and cone transducin alpha-subunits.
Deng WT, Sakurai K, Liu J, Dinculescu A, Li J, Pang J, Min SH, Chiodo VA, Boye SL, Chang B, Kefalov VJ, Hauswirth WW. Deng WT, et al. Among authors: pang j. Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17681-6. doi: 10.1073/pnas.0901382106. Epub 2009 Oct 6. Proc Natl Acad Sci U S A. 2009. PMID: 19815523 Free PMC article.
Restoration of cone vision in a mouse model of achromatopsia.
Alexander JJ, Umino Y, Everhart D, Chang B, Min SH, Li Q, Timmers AM, Hawes NL, Pang JJ, Barlow RB, Hauswirth WW. Alexander JJ, et al. Among authors: pang jj. Nat Med. 2007 Jun;13(6):685-7. doi: 10.1038/nm1596. Epub 2007 May 21. Nat Med. 2007. PMID: 17515894 Free PMC article.
Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics.
Cideciyan AV, Aleman TS, Boye SL, Schwartz SB, Kaushal S, Roman AJ, Pang JJ, Sumaroka A, Windsor EA, Wilson JM, Flotte TR, Fishman GA, Heon E, Stone EM, Byrne BJ, Jacobson SG, Hauswirth WW. Cideciyan AV, et al. Among authors: pang jj. Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15112-7. doi: 10.1073/pnas.0807027105. Epub 2008 Sep 22. Proc Natl Acad Sci U S A. 2008. PMID: 18809924 Free PMC article. Clinical Trial.
Gene-based Therapy in a Mouse Model of Blue Cone Monochromacy.
Zhang Y, Deng WT, Du W, Zhu P, Li J, Xu F, Sun J, Gerstner CD, Baehr W, Boye SL, Zhao C, Hauswirth WW, Pang JJ. Zhang Y, et al. Among authors: pang jj. Sci Rep. 2017 Jul 27;7(1):6690. doi: 10.1038/s41598-017-06982-7. Sci Rep. 2017. PMID: 28751656 Free PMC article.
Cone phosphodiesterase-6α' restores rod function and confers distinct physiological properties in the rod phosphodiesterase-6β-deficient rd10 mouse.
Deng WT, Sakurai K, Kolandaivelu S, Kolesnikov AV, Dinculescu A, Li J, Zhu P, Liu X, Pang J, Chiodo VA, Boye SL, Chang B, Ramamurthy V, Kefalov VJ, Hauswirth WW. Deng WT, et al. Among authors: pang j. J Neurosci. 2013 Jul 17;33(29):11745-53. doi: 10.1523/JNEUROSCI.1536-13.2013. J Neurosci. 2013. PMID: 23864662 Free PMC article.
Gene therapy restores vision-dependent behavior as well as retinal structure and function in a mouse model of RPE65 Leber congenital amaurosis.
Pang JJ, Chang B, Kumar A, Nusinowitz S, Noorwez SM, Li J, Rani A, Foster TC, Chiodo VA, Doyle T, Li H, Malhotra R, Teusner JT, McDowell JH, Min SH, Li Q, Kaushal S, Hauswirth WW. Pang JJ, et al. Mol Ther. 2006 Mar;13(3):565-72. doi: 10.1016/j.ymthe.2005.09.001. Epub 2005 Oct 11. Mol Ther. 2006. PMID: 16223604 Free article.
Achromatopsia as a potential candidate for gene therapy.
Pang JJ, Alexander J, Lei B, Deng W, Zhang K, Li Q, Chang B, Hauswirth WW. Pang JJ, et al. Adv Exp Med Biol. 2010;664:639-46. doi: 10.1007/978-1-4419-1399-9_73. Adv Exp Med Biol. 2010. PMID: 20238068 Free PMC article.
4,025 results