Kimura A - Search Results

1

Novel mechanisms of trafficking defect caused by KCNQ1 mutations found in long QT syndrome.

Sato A, Arimura T, Makita N, Ishikawa T, Aizawa Y, Ushinohama H, Aizawa Y, Kimura A. Sato A, et al. Among authors: kimura a. J Biol Chem. 2009 Dec 11;284(50):35122-33. doi: 10.1074/jbc.M109.017293. Epub 2009 Oct 13. J Biol Chem. 2009. PMID: 19825999 Free PMC article.

2

A mutant cardiac sodium channel with multiple biophysical defects associated with overlapping clinical features of Brugada syndrome and cardiac conduction disease.

Shirai N, Makita N, Sasaki K, Yokoi H, Sakuma I, Sakurada H, Akai J, Kimura A, Hiraoka M, Kitabatake A. Shirai N, et al. Among authors: kimura a. Cardiovasc Res. 2002 Feb 1;53(2):348-54. doi: 10.1016/s0008-6363(01)00494-1. Cardiovasc Res. 2002. PMID: 11827685

3

Titin mutations as the molecular basis for dilated cardiomyopathy.

Itoh-Satoh M, Hayashi T, Nishi H, Koga Y, Arimura T, Koyanagi T, Takahashi M, Hohda S, Ueda K, Nouchi T, Hiroe M, Marumo F, Imaizumi T, Yasunami M, Kimura A. Itoh-Satoh M, et al. Among authors: kimura a. Biochem Biophys Res Commun. 2002 Feb 22;291(2):385-93. doi: 10.1006/bbrc.2002.6448. Biochem Biophys Res Commun. 2002. PMID: 11846417

4

A Cypher/ZASP mutation associated with dilated cardiomyopathy alters the binding affinity to protein kinase C.

Arimura T, Hayashi T, Terada H, Lee SY, Zhou Q, Takahashi M, Ueda K, Nouchi T, Hohda S, Shibutani M, Hirose M, Chen J, Park JE, Yasunami M, Hayashi H, Kimura A. Arimura T, et al. Among authors: kimura a. J Biol Chem. 2004 Feb 20;279(8):6746-52. doi: 10.1074/jbc.M311849200. Epub 2003 Dec 3. J Biol Chem. 2004. PMID: 14660611 Free article.

5

Identification and functional analysis of a caveolin-3 mutation associated with familial hypertrophic cardiomyopathy.

Hayashi T, Arimura T, Ueda K, Shibata H, Hohda S, Takahashi M, Hori H, Koga Y, Oka N, Imaizumi T, Yasunami M, Kimura A. Hayashi T, et al. Among authors: kimura a. Biochem Biophys Res Commun. 2004 Jan 2;313(1):178-84. doi: 10.1016/j.bbrc.2003.11.101. Biochem Biophys Res Commun. 2004. PMID: 14672715

6

Functional characterization of a trafficking-defective HCN4 mutation, D553N, associated with cardiac arrhythmia.

Ueda K, Nakamura K, Hayashi T, Inagaki N, Takahashi M, Arimura T, Morita H, Higashiuesato Y, Hirano Y, Yasunami M, Takishita S, Yamashina A, Ohe T, Sunamori M, Hiraoka M, Kimura A. Ueda K, et al. Among authors: kimura a. J Biol Chem. 2004 Jun 25;279(26):27194-8. doi: 10.1074/jbc.M311953200. Epub 2004 Apr 30. J Biol Chem. 2004. PMID: 15123648 Free article.

7

Unexpected mexiletine responses of a mutant cardiac Na+ channel implicate the selectivity filter as a structural determinant of antiarrhythmic drug access.

Sasaki K, Makita N, Sunami A, Sakurada H, Shirai N, Yokoi H, Kimura A, Tohse N, Hiraoka M, Kitabatake A. Sasaki K, et al. Among authors: kimura a. Mol Pharmacol. 2004 Aug;66(2):330-6. doi: 10.1124/mol.66.2.330. Mol Pharmacol. 2004. PMID: 15266024

8

Truncated KCNQ1 mutant, A178fs/105, forms hetero-multimer channel with wild-type causing a dominant-negative suppression due to trafficking defect.

Aizawa Y, Ueda K, Wu LM, Inagaki N, Hayashi T, Takahashi M, Ohta M, Kawano S, Hirano Y, Yasunami M, Aizawa Y, Kimura A, Hiraoka M. Aizawa Y, et al. Among authors: kimura a. FEBS Lett. 2004 Sep 10;574(1-3):145-50. doi: 10.1016/j.febslet.2004.08.018. FEBS Lett. 2004. PMID: 15358555 Free article.

9

Novel C-terminus frameshift mutation, 1122fs/147, of HERG in LQT2: additional amino acids generated by frameshift cause accelerated inactivation.

Sasano T, Ueda K, Orikabe M, Hirano Y, Kawano S, Yasunami M, Isobe M, Kimura A, Hiraoka M. Sasano T, et al. Among authors: kimura a. J Mol Cell Cardiol. 2004 Dec;37(6):1205-11. doi: 10.1016/j.yjmcc.2004.09.010. J Mol Cell Cardiol. 2004. PMID: 15572050

10

Tcap gene mutations in hypertrophic cardiomyopathy and dilated cardiomyopathy.

Hayashi T, Arimura T, Itoh-Satoh M, Ueda K, Hohda S, Inagaki N, Takahashi M, Hori H, Yasunami M, Nishi H, Koga Y, Nakamura H, Matsuzaki M, Choi BY, Bae SW, You CW, Han KH, Park JE, Knöll R, Hoshijima M, Chien KR, Kimura A. Hayashi T, et al. Among authors: kimura a. J Am Coll Cardiol. 2004 Dec 7;44(11):2192-201. doi: 10.1016/j.jacc.2004.08.058. J Am Coll Cardiol. 2004. PMID: 15582318 Free article.

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