Henley C 3rd - Search Results

1

Metabolism-guided discovery of a potent and orally bioavailable urea-based calcimimetic for the treatment of secondary hyperparathyroidism.

Wehn PM, Harrington PE, Carlson TJ, Davis J, Deprez P, Fotsch CH, Grillo MP, Lu JY, Morony S, Pattabiraman K, Poon SF, Reagan JD, St Jean DJ Jr, Temal T, Wang M, Yang Y, Henley C 3rd, Lively SE. Wehn PM, et al. Among authors: henley c 3rd. Bioorg Med Chem Lett. 2013 Dec 15;23(24):6625-8. doi: 10.1016/j.bmcl.2013.10.050. Epub 2013 Oct 31. Bioorg Med Chem Lett. 2013. PMID: 24215889

2

Discovery of a calcimimetic with differential effects on parathyroid hormone and calcitonin secretion.

Henley C 3rd, Yang Y, Davis J, Lu JY, Morony S, Fan W, Florio M, Sun B, Shatzen E, Pretorius JK, Richards WG, St Jean DJ Jr, Fotsch C, Reagan JD. Henley C 3rd, et al. J Pharmacol Exp Ther. 2011 Jun;337(3):681-91. doi: 10.1124/jpet.110.178681. Epub 2011 Mar 21. J Pharmacol Exp Ther. 2011. PMID: 21422163

3

The discovery of an orally efficacious positive allosteric modulator of the calcium sensing receptor containing a dibenzylamine core.

Harrington PE, St Jean DJ Jr, Clarine J, Coulter TS, Croghan M, Davenport A, Davis J, Ghiron C, Hutchinson J, Kelly MG, Lott F, Lu JY, Martin D, Morony S, Poon SF, Portero-Larragueta E, Reagan JD, Regal KA, Tasker A, Wang M, Yang Y, Yao G, Zeng Q, Henley C 3rd, Fotsch C. Harrington PE, et al. Among authors: henley c 3rd. Bioorg Med Chem Lett. 2010 Sep 15;20(18):5544-7. doi: 10.1016/j.bmcl.2010.07.060. Epub 2010 Aug 12. Bioorg Med Chem Lett. 2010. PMID: 20708930

4

Discovery and optimization of substituted 1-(1-phenyl-1H-pyrazol-3-yl)methanamines as potent and efficacious type II calcimimetics.

Poon SF, St Jean DJ Jr, Harrington PE, Henley C 3rd, Davis J, Morony S, Lott FD, Reagan JD, Lu JY, Yang Y, Fotsch C. Poon SF, et al. Among authors: henley c 3rd. J Med Chem. 2009 Nov 12;52(21):6535-8. doi: 10.1021/jm9012278. J Med Chem. 2009. PMID: 19835382

5

Postnatal development of 2f1-f2 otoacoustic emissions in pigmented rat.

Henley CM 3rd, Owings MH, Stagner BB, Martin GK, Lonsbury-Martin BL. Henley CM 3rd, et al. Hear Res. 1990 Jan;43(2-3):141-8. doi: 10.1016/0378-5955(90)90223-c. Hear Res. 1990. PMID: 2312410

6

Inhibition of renal ornithine decarboxylase by aminoglycoside antibiotics in vitro.

Henley CM 3rd, Mahran LG, Schacht J. Henley CM 3rd, et al. Biochem Pharmacol. 1988 May 1;37(9):1679-82. doi: 10.1016/0006-2952(88)90427-3. Biochem Pharmacol. 1988. PMID: 3377830 Free article.

7

Pharmacokinetics of aminoglycoside antibiotics in blood, inner-ear fluids and tissues and their relationship to ototoxicity.

Henley CM 3rd, Schacht J. Henley CM 3rd, et al. Audiology. 1988;27(3):137-46. doi: 10.3109/00206098809081584. Audiology. 1988. PMID: 3044302 Review.

8

Inhibition of inner ear ornithine decarboxylase by neomycin in-vitro.

Henley CM 3rd, Gerhardt HJ, Schacht J. Henley CM 3rd, et al. Brain Res Bull. 1987 Dec;19(6):695-8. doi: 10.1016/0361-9230(87)90056-6. Brain Res Bull. 1987. PMID: 3125950 Free article.

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