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Page 1
Angiotensin-II type 1 receptor-mediated Janus kinase 2 activation induces liver fibrosis.
Granzow M, Schierwagen R, Klein S, Kowallick B, Huss S, Linhart M, Mazar IG, Görtzen J, Vogt A, Schildberg FA, Gonzalez-Carmona MA, Wojtalla A, Krämer B, Nattermann J, Siegmund SV, Werner N, Fürst DO, Laleman W, Knolle P, Shah VH, Sauerbruch T, Trebicka J. Granzow M, et al. Hepatology. 2014 Jul;60(1):334-48. doi: 10.1002/hep.27117. Epub 2014 May 6. Hepatology. 2014. PMID: 24619965 Free PMC article.
Role of cannabinoid receptors in alcoholic hepatic injury: steatosis and fibrogenesis are increased in CB2 receptor-deficient mice and decreased in CB1 receptor knockouts.
Trebicka J, Racz I, Siegmund SV, Cara E, Granzow M, Schierwagen R, Klein S, Wojtalla A, Hennenberg M, Huss S, Fischer HP, Heller J, Zimmer A, Sauerbruch T. Trebicka J, et al. Among authors: granzow m. Liver Int. 2011 Jul;31(6):860-70. doi: 10.1111/j.1478-3231.2011.02496.x. Epub 2011 Mar 8. Liver Int. 2011. PMID: 21645218
The endocannabinoid N-arachidonoyl dopamine (NADA) selectively induces oxidative stress-mediated cell death in hepatic stellate cells but not in hepatocytes.
Wojtalla A, Herweck F, Granzow M, Klein S, Trebicka J, Huss S, Lerner R, Lutz B, Schildberg FA, Knolle PA, Sauerbruch T, Singer MV, Zimmer A, Siegmund SV. Wojtalla A, et al. Among authors: granzow m. Am J Physiol Gastrointest Liver Physiol. 2012 Apr 15;302(8):G873-87. doi: 10.1152/ajpgi.00241.2011. Epub 2012 Feb 2. Am J Physiol Gastrointest Liver Physiol. 2012. PMID: 22301114 Free article.
Atorvastatin inhibits proliferation and apoptosis, but induces senescence in hepatic myofibroblasts and thereby attenuates hepatic fibrosis in rats.
Klein S, Klösel J, Schierwagen R, Körner C, Granzow M, Huss S, Mazar IG, Weber S, van den Ven PF, Pieper-Fürst U, Fürst DO, Nattermann J, Lammert F, Sauerbruch T, Trebicka J. Klein S, et al. Among authors: granzow m. Lab Invest. 2012 Oct;92(10):1440-50. doi: 10.1038/labinvest.2012.106. Epub 2012 Aug 13. Lab Invest. 2012. PMID: 22890553 Free article.
Statins activate the canonical hedgehog-signaling and aggravate non-cirrhotic portal hypertension, but inhibit the non-canonical hedgehog signaling and cirrhotic portal hypertension.
Uschner FE, Ranabhat G, Choi SS, Granzow M, Klein S, Schierwagen R, Raskopf E, Gautsch S, van der Ven PF, Fürst DO, Strassburg CP, Sauerbruch T, Diehl AM, Trebicka J. Uschner FE, et al. Among authors: granzow m. Sci Rep. 2015 Sep 28;5:14573. doi: 10.1038/srep14573. Sci Rep. 2015. PMID: 26412302 Free PMC article.
TGR(mREN2)27 rats develop non-alcoholic fatty liver disease-associated portal hypertension responsive to modulations of Janus-kinase 2 and Mas receptor.
Klein S, Kleine CE, Pieper A, Granzow M, Gautsch S, Himmit M, Kahrmann K, Schierwagen R, Uschner FE, Magdaleno F, Naoum ME, Kristiansen G, Walther T, Bader M, Sauerbruch T, Trebicka J. Klein S, et al. Among authors: granzow m. Sci Rep. 2019 Aug 12;9(1):11598. doi: 10.1038/s41598-019-48024-4. Sci Rep. 2019. PMID: 31406138 Free PMC article.
59 results