Nowlin D - Search Results

1

Azaindole hydroxamic acids are potent HIV-1 integrase inhibitors.

Plewe MB, Butler SL, Dress KR, Hu Q, Johnson TW, Kuehler JE, Kuki A, Lam H, Liu W, Nowlin D, Peng Q, Rahavendran SV, Tanis SP, Tran KT, Wang H, Yang A, Zhang J. Plewe MB, et al. Among authors: nowlin d. J Med Chem. 2009 Nov 26;52(22):7211-9. doi: 10.1021/jm900862n. J Med Chem. 2009. PMID: 19873974

2

Synthesis and SAR of N-benzoyl-L-biphenylalanine derivatives: discovery of TR-14035, a dual alpha(4)beta(7)/alpha(4)beta(1) integrin antagonist.

Sircar I, Gudmundsson KS, Martin R, Liang J, Nomura S, Jayakumar H, Teegarden BR, Nowlin DM, Cardarelli PM, Mah JR, Connell S, Griffith RC, Lazarides E. Sircar I, et al. Among authors: nowlin dm. Bioorg Med Chem. 2002 Jun;10(6):2051-66. doi: 10.1016/s0968-0896(02)00021-4. Bioorg Med Chem. 2002. PMID: 11937364

3

Cyclic RGD peptide inhibits alpha 4 beta 1 interaction with connecting segment 1 and vascular cell adhesion molecule.

Cardarelli PM, Cobb RR, Nowlin DM, Scholz W, Gorcsan F, Moscinski M, Yasuhara M, Chiang SL, Lobl TJ. Cardarelli PM, et al. Among authors: nowlin dm. J Biol Chem. 1994 Jul 15;269(28):18668-73. J Biol Chem. 1994. PMID: 7518441 Free article.

4

A novel cyclic pentapeptide inhibits alpha 4 beta 1 and alpha 5 beta 1 integrin-mediated cell adhesion.

Nowlin DM, Gorcsan F, Moscinski M, Chiang SL, Lobl TJ, Cardarelli PM. Nowlin DM, et al. J Biol Chem. 1993 Sep 25;268(27):20352-9. J Biol Chem. 1993. PMID: 7690755 Free article.

5

Identification of Cys255 in HIF-1α as a novel site for development of covalent inhibitors of HIF-1α/ARNT PasB domain protein-protein interaction.

Cardoso R, Love R, Nilsson CL, Bergqvist S, Nowlin D, Yan J, Liu KK, Zhu J, Chen P, Deng YL, Dyson HJ, Greig MJ, Brooun A. Cardoso R, et al. Among authors: nowlin d. Protein Sci. 2012 Dec;21(12):1885-96. doi: 10.1002/pro.2172. Epub 2012 Nov 9. Protein Sci. 2012. PMID: 23033253 Free PMC article.

6

Structural and biophysical characterization of XIAP BIR3 G306E mutant: insights in protein dynamics and application for fragment-based drug design.

Moore CD, Wu H, Bolaños B, Bergqvist S, Brooun A, Pauly T, Nowlin D. Moore CD, et al. Among authors: nowlin d. Chem Biol Drug Des. 2009 Sep;74(3):212-23. doi: 10.1111/j.1747-0285.2009.00862.x. Epub 2009 Jul 29. Chem Biol Drug Des. 2009. PMID: 19660030

7

Analysing the output from primary screening.

Nowlin D, Bingham P, Berridge A, Gribbon P, Laflin P, Sewing A. Nowlin D, et al. Comb Chem High Throughput Screen. 2006 Jun;9(5):331-7. doi: 10.2174/138620706777452401. Comb Chem High Throughput Screen. 2006. PMID: 16787146

8

Inhibition of tyrosine kinases blocks adhesion-induced T-cell coactivation without interfering with T-cell adhesion to endothelial cell-surface ligands.

Nowlin DM, Cardarelli PM, Young L, Mah J, Felts KA, Mastrangelo M, Cobb RR. Nowlin DM, et al. Inflammation. 2002 Feb;26(1):31-43. doi: 10.1023/a:1014421829234. Inflammation. 2002. PMID: 11936754

9

Targeting S-adenosylmethionine biosynthesis with a novel allosteric inhibitor of Mat2A.

Quinlan CL, Kaiser SE, Bolaños B, Nowlin D, Grantner R, Karlicek-Bryant S, Feng JL, Jenkinson S, Freeman-Cook K, Dann SG, Wang X, Wells PA, Fantin VR, Stewart AE, Grant SK. Quinlan CL, et al. Among authors: nowlin d. Nat Chem Biol. 2017 Jul;13(7):785-792. doi: 10.1038/nchembio.2384. Epub 2017 May 29. Nat Chem Biol. 2017. PMID: 28553945

10

Sites of covalent modification in Trg, a sensory transducer of Escherichia coli.

Nowlin DM, Bollinger J, Hazelbauer GL. Nowlin DM, et al. J Biol Chem. 1987 May 5;262(13):6039-45. J Biol Chem. 1987. PMID: 3032955 Free article.

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