Benet LZ - Search Results

1

The drug transporter-metabolism alliance: uncovering and defining the interplay.

Benet LZ. Benet LZ. Mol Pharm. 2009 Nov-Dec;6(6):1631-43. doi: 10.1021/mp900253n. Mol Pharm. 2009. PMID: 19874004 Free PMC article. Review.

2

Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

Wacher VJ, Wu CY, Benet LZ. Wacher VJ, et al. Among authors: benet lz. Mol Carcinog. 1995 Jul;13(3):129-34. doi: 10.1002/mc.2940130302. Mol Carcinog. 1995. PMID: 7619215 Review. No abstract available.

3

Tacrolimus oral bioavailability doubles with coadministration of ketoconazole.

Floren LC, Bekersky I, Benet LZ, Mekki Q, Dressler D, Lee JW, Roberts JP, Hebert MF. Floren LC, et al. Among authors: benet lz. Clin Pharmacol Ther. 1997 Jul;62(1):41-9. doi: 10.1016/S0009-9236(97)90150-8. Clin Pharmacol Ther. 1997. PMID: 9246018

4

Effects of ketoconazole on the intestinal metabolism, transport and oral bioavailability of K02, a novel vinylsulfone peptidomimetic cysteine protease inhibitor and a P450 3A, P-glycoprotein dual substrate, in male Sprague-Dawley rats.

Zhang Y, Hsieh Y, Izumi T, Lin ET, Benet LZ. Zhang Y, et al. Among authors: benet lz. J Pharmacol Exp Ther. 1998 Oct;287(1):246-52. J Pharmacol Exp Ther. 1998. PMID: 9765344

5

Grapefruit juice activates P-glycoprotein-mediated drug transport.

Soldner A, Christians U, Susanto M, Wacher VJ, Silverman JA, Benet LZ. Soldner A, et al. Among authors: benet lz. Pharm Res. 1999 Apr;16(4):478-85. doi: 10.1023/a:1011902625609. Pharm Res. 1999. PMID: 10227700

6

Intestinal MDR transport proteins and P-450 enzymes as barriers to oral drug delivery.

Benet LZ, Izumi T, Zhang Y, Silverman JA, Wacher VJ. Benet LZ, et al. J Control Release. 1999 Nov 1;62(1-2):25-31. doi: 10.1016/s0168-3659(99)00034-6. J Control Release. 1999. PMID: 10518631

7

The drug efflux-metabolism alliance: biochemical aspects.

Benet LZ, Cummins CL. Benet LZ, et al. Adv Drug Deliv Rev. 2001 Oct 1;50 Suppl 1:S3-11. doi: 10.1016/s0169-409x(01)00178-8. Adv Drug Deliv Rev. 2001. PMID: 11576692 Review.

8

Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4.

Cummins CL, Jacobsen W, Benet LZ. Cummins CL, et al. Among authors: benet lz. J Pharmacol Exp Ther. 2002 Mar;300(3):1036-45. doi: 10.1124/jpet.300.3.1036. J Pharmacol Exp Ther. 2002. PMID: 11861813

9

In vivo modulation of intestinal CYP3A metabolism by P-glycoprotein: studies using the rat single-pass intestinal perfusion model.

Cummins CL, Salphati L, Reid MJ, Benet LZ. Cummins CL, et al. Among authors: benet lz. J Pharmacol Exp Ther. 2003 Apr;305(1):306-14. doi: 10.1124/jpet.102.044719. J Pharmacol Exp Ther. 2003. PMID: 12649383

10

Transporter-enzyme interactions: implications for predicting drug-drug interactions from in vitro data.

Benet LZ, Cummins CL, Wu CY. Benet LZ, et al. Curr Drug Metab. 2003 Oct;4(5):393-8. doi: 10.2174/1389200033489389. Curr Drug Metab. 2003. PMID: 14529371 Review.

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