Lloyd P - Search Results

1

The minimum anticipated biological effect level (MABEL) for selection of first human dose in clinical trials with monoclonal antibodies.

Muller PY, Milton M, Lloyd P, Sims J, Brennan FR. Muller PY, et al. Among authors: lloyd p. Curr Opin Biotechnol. 2009 Dec;20(6):722-9. doi: 10.1016/j.copbio.2009.10.013. Epub 2009 Nov 5. Curr Opin Biotechnol. 2009. PMID: 19896825 Review.

2

On setting the first dose in man: quantitating biotherapeutic drug-target binding through pharmacokinetic and pharmacodynamic models.

Lowe PJ, Tannenbaum S, Wu K, Lloyd P, Sims J. Lowe PJ, et al. Among authors: lloyd p. Basic Clin Pharmacol Toxicol. 2010 Mar;106(3):195-209. doi: 10.1111/j.1742-7843.2009.00513.x. Epub 2009 Dec 29. Basic Clin Pharmacol Toxicol. 2010. PMID: 20050847 Free article. Review.

3

Integrated pharmacokinetic, pharmacodynamic and immunogenicity profiling of an anti-CCL21 monoclonal antibody in cynomolgus monkeys.

Dudal S, Subramanian K, Flandre T, Law WS, Lowe PJ, Skerjanec A, Genin JC, Duval M, Piequet A, Cordier A, Jarai G, Van Heeke G, Taplin S, Krantz C, Jones S, Warren AP, Brennan FR, Sims J, Lloyd P. Dudal S, et al. Among authors: lloyd p. MAbs. 2015;7(5):829-37. doi: 10.1080/19420862.2015.1060384. MAbs. 2015. PMID: 26230385 Free PMC article.

4

Absolute bioavailability and pharmacokinetics of valsartan, an angiotensin II receptor antagonist, in man.

Flesch G, Müller P, Lloyd P. Flesch G, et al. Among authors: lloyd p. Eur J Clin Pharmacol. 1997;52(2):115-20. doi: 10.1007/s002280050259. Eur J Clin Pharmacol. 1997. PMID: 9174680 Clinical Trial.

5

Evaluation of dried blood spots for the quantification of therapeutic monoclonal antibodies and detection of anti-drug antibodies.

Kaendler K, Warren A, Lloyd P, Sims J, Sickert D. Kaendler K, et al. Among authors: lloyd p. Bioanalysis. 2013 Mar;5(5):613-22. doi: 10.4155/bio.13.11. Bioanalysis. 2013. PMID: 23425276

6

Secukinumab, a fully human anti-interleukin-17A monoclonal antibody, exhibits minimal immunogenicity in patients with moderate-to-severe plaque psoriasis.

Reich K, Blauvelt A, Armstrong A, Langley RG, Fox T, Huang J, Papavassilis C, Liang E, Lloyd P, Bruin G. Reich K, et al. Among authors: lloyd p. Br J Dermatol. 2017 Mar;176(3):752-758. doi: 10.1111/bjd.14965. Epub 2016 Nov 22. Br J Dermatol. 2017. PMID: 27518376

7

Ethnic sensitivity assessment - pharmacokinetic comparability between Japanese and non-Japanese healthy subjects on selected mAbs.

Matsushima S, Huang Y, Suzuki H, Nishino J, Lloyd P. Matsushima S, et al. Among authors: lloyd p. Expert Opin Drug Metab Toxicol. 2015 Feb;11(2):179-91. doi: 10.1517/17425255.2015.990438. Epub 2014 Dec 18. Expert Opin Drug Metab Toxicol. 2015. PMID: 25519513

8

Use of generic LC-MS/MS assays to characterize atypical PK profile of a biotherapeutic monoclonal antibody.

Law WS, Genin JC, Miess C, Treton G, Warren AP, Lloyd P, Dudal S, Krantz C. Law WS, et al. Among authors: lloyd p. Bioanalysis. 2014;6(23):3225-35. doi: 10.4155/bio.14.167. Bioanalysis. 2014. PMID: 25529889

9

Pharmacokinetics of the monohydroxy derivative of oxcarbazepine and its enantiomers after a single intravenous dose given as racemate compared with a single oral dose of oxcarbazepine.

Flesch G, Czendlik C, Renard D, Lloyd P. Flesch G, et al. Among authors: lloyd p. Drug Metab Dispos. 2011 Jun;39(6):1103-10. doi: 10.1124/dmd.109.030593. Epub 2011 Mar 9. Drug Metab Dispos. 2011. PMID: 21389120 Clinical Trial.

10

Pharmacokinetics of serelaxin in patients with hepatic impairment: a single-dose, open-label, parallel group study.

Kobalava Z, Villevalde S, Kotovskaya Y, Hinrichsen H, Petersen-Sylla M, Zaehringer A, Pang Y, Rajman I, Canadi J, Dahlke M, Lloyd P, Halabi A. Kobalava Z, et al. Among authors: lloyd p. Br J Clin Pharmacol. 2015 Jun;79(6):937-45. doi: 10.1111/bcp.12572. Br J Clin Pharmacol. 2015. PMID: 25511105 Free PMC article. Clinical Trial.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

413 results

Search Page

Filters