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Pharmacologic inhibition of MEK signaling prevents growth of canine hemangiosarcoma.
Andersen NJ, Nickoloff BJ, Dykema KJ, Boguslawski EA, Krivochenitser RI, Froman RE, Dawes MJ, Baker LH, Thomas DG, Kamstock DA, Kitchell BE, Furge KA, Duesbery NS. Andersen NJ, et al. Mol Cancer Ther. 2013 Sep;12(9):1701-14. doi: 10.1158/1535-7163.MCT-12-0893. Epub 2013 Jun 26. Mol Cancer Ther. 2013. PMID: 23804705 Free PMC article.
A highly invasive human glioblastoma pre-clinical model for testing therapeutics.
Xie Q, Thompson R, Hardy K, DeCamp L, Berghuis B, Sigler R, Knudsen B, Cottingham S, Zhao P, Dykema K, Cao B, Resau J, Hay R, Vande Woude GF. Xie Q, et al. Among authors: dykema k. J Transl Med. 2008 Dec 3;6:77. doi: 10.1186/1479-5876-6-77. J Transl Med. 2008. PMID: 19055779 Free PMC article.
Reversible epithelial to mesenchymal transition and acquired resistance to sunitinib in patients with renal cell carcinoma: evidence from a xenograft study.
Hammers HJ, Verheul HM, Salumbides B, Sharma R, Rudek M, Jaspers J, Shah P, Ellis L, Shen L, Paesante S, Dykema K, Furge K, Teh BT, Netto G, Pili R. Hammers HJ, et al. Among authors: dykema k. Mol Cancer Ther. 2010 Jun;9(6):1525-35. doi: 10.1158/1535-7163.MCT-09-1106. Epub 2010 May 25. Mol Cancer Ther. 2010. PMID: 20501804 Free PMC article.
Disruption of tubular Flcn expression as a mouse model for renal tumor induction.
Chen J, Huang D, Rubera I, Futami K, Wang P, Zickert P, Khoo SK, Dykema K, Zhao P, Petillo D, Cao B, Zhang Z, Si S, Schoen SR, Yang XJ, Zhou M, Xiao GQ, Wu G, Nordenskjöld M, Tauc M, Williams BO, Furge KA, Teh BT. Chen J, et al. Among authors: dykema k. Kidney Int. 2015 Nov;88(5):1057-69. doi: 10.1038/ki.2015.177. Epub 2015 Jun 17. Kidney Int. 2015. PMID: 26083655 Free article.
57 results