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A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population.
Asano K, Matsushita T, Umeno J, Hosono N, Takahashi A, Kawaguchi T, Matsumoto T, Matsui T, Kakuta Y, Kinouchi Y, Shimosegawa T, Hosokawa M, Arimura Y, Shinomura Y, Kiyohara Y, Tsunoda T, Kamatani N, Iida M, Nakamura Y, Kubo M. Asano K, et al. Among authors: takahashi a. Nat Genet. 2009 Dec;41(12):1325-9. doi: 10.1038/ng.482. Epub 2009 Nov 15. Nat Genet. 2009. PMID: 19915573
Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis.
Suzuki A, Yamada R, Chang X, Tokuhiro S, Sawada T, Suzuki M, Nagasaki M, Nakayama-Hamada M, Kawaida R, Ono M, Ohtsuki M, Furukawa H, Yoshino S, Yukioka M, Tohma S, Matsubara T, Wakitani S, Teshima R, Nishioka Y, Sekine A, Iida A, Takahashi A, Tsunoda T, Nakamura Y, Yamamoto K. Suzuki A, et al. Among authors: takahashi a. Nat Genet. 2003 Aug;34(4):395-402. doi: 10.1038/ng1206. Nat Genet. 2003. PMID: 12833157
An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis.
Tokuhiro S, Yamada R, Chang X, Suzuki A, Kochi Y, Sawada T, Suzuki M, Nagasaki M, Ohtsuki M, Ono M, Furukawa H, Nagashima M, Yoshino S, Mabuchi A, Sekine A, Saito S, Takahashi A, Tsunoda T, Nakamura Y, Yamamoto K. Tokuhiro S, et al. Among authors: takahashi a. Nat Genet. 2003 Dec;35(4):341-8. doi: 10.1038/ng1267. Epub 2003 Nov 9. Nat Genet. 2003. PMID: 14608356
Analysis of single-nucleotide polymorphisms in Japanese rheumatoid arthritis patients shows additional susceptibility markers besides the classic shared epitope susceptibility sequences.
Kochi Y, Yamada R, Kobayashi K, Takahashi A, Suzuki A, Sekine A, Mabuchi A, Akiyama F, Tsunoda T, Nakamura Y, Yamamoto K. Kochi Y, et al. Among authors: takahashi a. Arthritis Rheum. 2004 Jan;50(1):63-71. doi: 10.1002/art.11366. Arthritis Rheum. 2004. PMID: 14730600 Free article.
Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes.
Kanazawa A, Tsukada S, Sekine A, Tsunoda T, Takahashi A, Kashiwagi A, Tanaka Y, Babazono T, Matsuda M, Kaku K, Iwamoto Y, Kawamori R, Kikkawa R, Nakamura Y, Maeda S. Kanazawa A, et al. Among authors: takahashi a. Am J Hum Genet. 2004 Nov;75(5):832-43. doi: 10.1086/425340. Epub 2004 Sep 21. Am J Hum Genet. 2004. PMID: 15386214 Free PMC article.
A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities.
Kochi Y, Yamada R, Suzuki A, Harley JB, Shirasawa S, Sawada T, Bae SC, Tokuhiro S, Chang X, Sekine A, Takahashi A, Tsunoda T, Ohnishi Y, Kaufman KM, Kang CP, Kang C, Otsubo S, Yumura W, Mimori A, Koike T, Nakamura Y, Sasazuki T, Yamamoto K. Kochi Y, et al. Among authors: takahashi a. Nat Genet. 2005 May;37(5):478-85. doi: 10.1038/ng1540. Epub 2005 Apr 17. Nat Genet. 2005. PMID: 15838509 Free PMC article.
Coding SNP in tenascin-C Fn-III-D domain associates with adult asthma.
Matsuda A, Hirota T, Akahoshi M, Shimizu M, Tamari M, Miyatake A, Takahashi A, Nakashima K, Takahashi N, Obara K, Yuyama N, Doi S, Kamogawa Y, Enomoto T, Ohshima K, Tsunoda T, Miyatake S, Fujita K, Kusakabe M, Izuhara K, Nakamura Y, Hopkin J, Shirakawa T. Matsuda A, et al. Among authors: takahashi n, takahashi a. Hum Mol Genet. 2005 Oct 1;14(19):2779-86. doi: 10.1093/hmg/ddi311. Epub 2005 Aug 22. Hum Mol Genet. 2005. PMID: 16115819
Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease.
Yamazaki K, McGovern D, Ragoussis J, Paolucci M, Butler H, Jewell D, Cardon L, Takazoe M, Tanaka T, Ichimori T, Saito S, Sekine A, Iida A, Takahashi A, Tsunoda T, Lathrop M, Nakamura Y. Yamazaki K, et al. Among authors: takahashi a. Hum Mol Genet. 2005 Nov 15;14(22):3499-506. doi: 10.1093/hmg/ddi379. Epub 2005 Oct 12. Hum Mol Genet. 2005. PMID: 16221758
4,923 results