Downes CP - Search Results

1

Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN.

Davidson L, Maccario H, Perera NM, Yang X, Spinelli L, Tibarewal P, Glancy B, Gray A, Weijer CJ, Downes CP, Leslie NR. Davidson L, et al. Among authors: downes cp. Oncogene. 2010 Feb 4;29(5):687-97. doi: 10.1038/onc.2009.384. Epub 2009 Nov 16. Oncogene. 2010. PMID: 19915616 Free PMC article.

2

The tumour-suppressor function of PTEN requires an N-terminal lipid-binding motif.

Walker SM, Leslie NR, Perera NM, Batty IH, Downes CP. Walker SM, et al. Among authors: downes cp. Biochem J. 2004 Apr 15;379(Pt 2):301-7. doi: 10.1042/BJ20031839. Biochem J. 2004. PMID: 14711368 Free PMC article.

3

PTEN function: how normal cells control it and tumour cells lose it.

Leslie NR, Downes CP. Leslie NR, et al. Among authors: downes cp. Biochem J. 2004 Aug 15;382(Pt 1):1-11. doi: 10.1042/BJ20040825. Biochem J. 2004. PMID: 15193142 Free PMC article. Review.

4

Substrate specificity and acute regulation of the tumour suppressor phosphatase, PTEN.

Downes CP, Perera N, Ross S, Leslie NR. Downes CP, et al. Biochem Soc Symp. 2007;(74):69-80. doi: 10.1042/BSS0740069. Biochem Soc Symp. 2007. PMID: 17233581 Review.

5

PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration.

Leslie NR, Yang X, Downes CP, Weijer CJ. Leslie NR, et al. Among authors: downes cp. Curr Biol. 2007 Jan 23;17(2):115-25. doi: 10.1016/j.cub.2006.12.026. Curr Biol. 2007. PMID: 17240336 Free PMC article.

6

Stimulation of PI 3-kinase signaling via inhibition of the tumor suppressor phosphatase, PTEN.

Downes CP, Ross S, Maccario H, Perera N, Davidson L, Leslie NR. Downes CP, et al. Adv Enzyme Regul. 2007;47:184-94. doi: 10.1016/j.advenzreg.2006.12.018. Epub 2006 Dec 30. Adv Enzyme Regul. 2007. PMID: 17343901 Review. No abstract available.

7

PTEN is destabilized by phosphorylation on Thr366.

Maccario H, Perera NM, Davidson L, Downes CP, Leslie NR. Maccario H, et al. Among authors: downes cp. Biochem J. 2007 Aug 1;405(3):439-44. doi: 10.1042/BJ20061837. Biochem J. 2007. PMID: 17444818 Free PMC article.

8

Ubiquitination of PTEN (phosphatase and tensin homolog) inhibits phosphatase activity and is enhanced by membrane targeting and hyperosmotic stress.

Maccario H, Perera NM, Gray A, Downes CP, Leslie NR. Maccario H, et al. Among authors: downes cp. J Biol Chem. 2010 Apr 23;285(17):12620-8. doi: 10.1074/jbc.M109.072280. Epub 2010 Feb 22. J Biol Chem. 2010. PMID: 20177066 Free PMC article.

9

Redox regulation of PI 3-kinase signalling via inactivation of PTEN.

Leslie NR, Bennett D, Lindsay YE, Stewart H, Gray A, Downes CP. Leslie NR, et al. Among authors: downes cp. EMBO J. 2003 Oct 15;22(20):5501-10. doi: 10.1093/emboj/cdg513. EMBO J. 2003. PMID: 14532122 Free PMC article.

10

PTEN: The down side of PI 3-kinase signalling.

Leslie NR, Downes CP. Leslie NR, et al. Among authors: downes cp. Cell Signal. 2002 Apr;14(4):285-95. doi: 10.1016/s0898-6568(01)00234-0. Cell Signal. 2002. PMID: 11858936 Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

217 results

Search Page

Filters