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1H NMR structure and biological studies of the His23-->Cys mutant nucleocapsid protein of HIV-1 indicate that the conformation of the first zinc finger is critical for virus infectivity.
Déméné H, Dong CZ, Ottmann M, Rouyez MC, Jullian N, Morellet N, Mely Y, Darlix JL, Fournié-Zaluski MC, Saragosti S, et al. Déméné H, et al. Among authors: mely y. Biochemistry. 1994 Oct 4;33(39):11707-16. doi: 10.1021/bi00205a006. Biochemistry. 1994. PMID: 7918387
Structural and dynamic characterization of the aromatic amino acids of the human immunodeficiency virus type I nucleocapsid protein zinc fingers and their involvement in heterologous tRNA(Phe) binding: a steady-state and time-resolved fluorescence study.
Mély Y, Piémont E, Sorinas-Jimeno M, de Rocquigny H, Jullian N, Morellet N, Roques BP, Gérard D. Mély Y, et al. Biophys J. 1993 Oct;65(4):1513-22. doi: 10.1016/S0006-3495(93)81222-0. Biophys J. 1993. PMID: 8274645 Free PMC article.
Influence of the N- and C-terminal chains on the zinc-binding and conformational properties of the central zinc-finger structure of Moloney murine leukaemia virus nucleocapsid protein: a steady-state and time-resolved fluorescence study.
Mely Y, de Rocquigny H, Piémont E, Déméné H, Jullian N, Fournié-Zaluski MC, Roques B, Gérard D. Mely Y, et al. Biochim Biophys Acta. 1993 Jan 15;1161(1):6-18. doi: 10.1016/0167-4838(93)90189-x. Biochim Biophys Acta. 1993. PMID: 8422421
346 results