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Atorvastatin therapy lowers circulating cholesterol but not free radical activity in advance of identifiable clinical benefit in the treatment of mild-to-moderate AD.
Sparks DL, Sabbagh MN, Connor DJ, Lopez J, Launer LJ, Petanceska S, Browne P, Wassar D, Johnson-Traver S, Lochhead J, Ziolkowski C. Sparks DL, et al. Among authors: sabbagh mn. Curr Alzheimer Res. 2005 Jul;2(3):343-53. doi: 10.2174/1567205054367900. Curr Alzheimer Res. 2005. PMID: 15974900 Clinical Trial.
Is cholesterol a culprit in Alzheimer's disease?
Sparks DL, Sabbagh MN, Breitner JC, Hunsaker JC 3rd; AD Cholestrol-Lowering Treatment Trial Team and the Ancillary ADAPT: Cholestrol and Statin Parameters Work Group; Cache County and ADAPT Work Groups; Eastern Division of the Kentucky Medical Examiner's Group. Sparks DL, et al. Among authors: sabbagh mn. Int Psychogeriatr. 2003;15 Suppl 1:153-9. doi: 10.1017/S1041610203009128. Int Psychogeriatr. 2003. PMID: 16191233
555 results