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Page 1
Small molecule inhibitors of HIV RT Ribonuclease H.
Di Grandi M, Olson M, Prashad AS, Bebernitz G, Luckay A, Mullen S, Hu Y, Krishnamurthy G, Pitts K, O'Connell J. Di Grandi M, et al. Among authors: prashad as. Bioorg Med Chem Lett. 2010 Jan 1;20(1):398-402. doi: 10.1016/j.bmcl.2009.10.043. Epub 2009 Oct 15. Bioorg Med Chem Lett. 2010. PMID: 19939680
Optimization of 5-phenyl-3-pyridinecarbonitriles as PKCtheta inhibitors.
Boschelli DH, Wang D, Prashad AS, Subrath J, Wu B, Niu C, Lee J, Yang X, Brennan A, Chaudhary D. Boschelli DH, et al. Among authors: prashad as. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3623-6. doi: 10.1016/j.bmcl.2009.04.126. Epub 2009 May 3. Bioorg Med Chem Lett. 2009. PMID: 19447612
C-5 substituted heteroaryl-3-pyridinecarbonitriles as PKCtheta inhibitors: part II.
Prashad AS, Wang D, Subrath J, Wu B, Lin M, Zhang MY, Kagan N, Lee J, Yang X, Brennan A, Chaudhary D, Xu X, Leung L, Wang J, Boschelli DH. Prashad AS, et al. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5799-802. doi: 10.1016/j.bmcl.2009.07.113. Epub 2009 Jul 28. Bioorg Med Chem Lett. 2009. PMID: 19703774
Mechanistic understanding of the cysteine capping modifications of antibodies enables selective chemical engineering in live mammalian cells.
Zhong X, He T, Prashad AS, Wang W, Cohen J, Ferguson D, Tam AS, Sousa E, Lin L, Tchistiakova L, Gatto S, D'Antona A, Luan YT, Ma W, Zollner R, Zhou J, Arve B, Somers W, Kriz R. Zhong X, et al. Among authors: prashad as. J Biotechnol. 2017 Apr 20;248:48-58. doi: 10.1016/j.jbiotec.2017.03.006. Epub 2017 Mar 11. J Biotechnol. 2017. PMID: 28300660
Cysteine metabolic engineering and selective disulfide reduction produce superior antibody-drug-conjugates.
Procopio-Melino R, Kotch FW, Prashad AS, Gomes JM, Wang W, Arve B, Dawdy A, Chen L, Sperry J, Hosselet C, He T, Kriz R, Lin L, Marquette K, Tchistiakova L, Somers W, Rouse JC, Zhong X. Procopio-Melino R, et al. Among authors: prashad as. Sci Rep. 2022 May 4;12(1):7262. doi: 10.1038/s41598-022-11344-z. Sci Rep. 2022. PMID: 35508689 Free PMC article.
11 results