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Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF.
Quigley M, Pereyra F, Nilsson B, Porichis F, Fonseca C, Eichbaum Q, Julg B, Jesneck JL, Brosnahan K, Imam S, Russell K, Toth I, Piechocka-Trocha A, Dolfi D, Angelosanto J, Crawford A, Shin H, Kwon DS, Zupkosky J, Francisco L, Freeman GJ, Wherry EJ, Kaufmann DE, Walker BD, Ebert B, Haining WN. Quigley M, et al. Among authors: crawford a. Nat Med. 2010 Oct;16(10):1147-51. doi: 10.1038/nm.2232. Epub 2010 Oct 3. Nat Med. 2010. PMID: 20890291 Free PMC article.
Inhibitory receptors: whose side are they on?
Crawford A, Wherry EJ. Crawford A, et al. Nat Immunol. 2007 Nov;8(11):1201-3. doi: 10.1038/ni1107-1201. Nat Immunol. 2007. PMID: 17952048 No abstract available.
Editorial: Therapeutic potential of targeting BTLA.
Crawford A, Wherry EJ. Crawford A, et al. J Leukoc Biol. 2009 Jul;86(1):5-8. doi: 10.1189/JLB.0209076. J Leukoc Biol. 2009. PMID: 19567411 Review. No abstract available.
1,526 results