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Page 1
Synthesis and pharmacological characterization of constrained analogues of Vestipitant as in vitro potent and orally active NK(1) receptor antagonists.
Sabbatini FM, Di Fabio R, Griffante C, Pentassuglia G, Zonzini L, Melotto S, Alvaro G, Capelli AM, Pippo L, Perdona' E, St Denis Y, Costa S, Corsi M. Sabbatini FM, et al. Bioorg Med Chem Lett. 2010 Jan 15;20(2):623-7. doi: 10.1016/j.bmcl.2009.11.078. Epub 2009 Nov 20. Bioorg Med Chem Lett. 2010. PMID: 19963378
Discovery process and characterization of novel carbohydrazide derivatives as potent and selective GHSR1a antagonists.
Sabbatini FM, Di Fabio R, Corsi M, Cavanni P, Bromidge SM, St-Denis Y, D'Adamo L, Contini S, Rinaldi M, Guery S, Savoia C, Mundi C, Perini B, Carpenter AJ, Dal Forno G, Faggioni F, Tessari M, Pavone F, Di Francesco C, Buson A, Mattioli M, Perdona' E, Melotto S. Sabbatini FM, et al. ChemMedChem. 2010 Sep 3;5(9):1450-5. doi: 10.1002/cmdc.201000185. ChemMedChem. 2010. PMID: 20593439 No abstract available.
Novel morpholine scaffolds as selective dopamine (DA) D3 receptor antagonists.
Micheli F, Cremonesi S, Semeraro T, Tarsi L, Tomelleri S, Cavanni P, Oliosi B, Perdonà E, Sava A, Zonzini L, Feriani A, Braggio S, Heidbreder C. Micheli F, et al. Among authors: perdona e. Bioorg Med Chem Lett. 2016 Feb 15;26(4):1329-32. doi: 10.1016/j.bmcl.2015.12.081. Epub 2016 Jan 5. Bioorg Med Chem Lett. 2016. PMID: 26786693
In vitro and in vivo characterization of the novel GABAB receptor positive allosteric modulator, 2-{1-[2-(4-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]-2-piperidinyl}ethanol (CMPPE).
Perdona' E, Costantini VJ, Tessari M, Martinelli P, Carignani C, Valerio E, Mok MH, Zonzini L, Visentini F, Gianotti M, Gordon L, Rocheville M, Corsi M, Capelli AM. Perdona' E, et al. Neuropharmacology. 2011 Oct-Nov;61(5-6):957-66. doi: 10.1016/j.neuropharm.2011.06.024. Epub 2011 Jul 5. Neuropharmacology. 2011. PMID: 21756923
Azabicyclo[3.1.0]hexane-1-carbohydrazides as potent and selective GHSR1a ligands presenting a specific in vivo behavior.
Sabbatini FM, Melotto S, Bernasconi G, Bromidge SM, D'Adamo L, Rinaldi M, Savoia C, Mundi C, Di Francesco C, Zonzini L, Costantini VJ, Perini B, Valerio E, Pozzan A, Perdonà E, Visentini F, Corsi M, Di Fabio R. Sabbatini FM, et al. Among authors: perdona e. ChemMedChem. 2011 Nov 4;6(11):1981-5. doi: 10.1002/cmdc.201100285. Epub 2011 Aug 10. ChemMedChem. 2011. PMID: 21834097 No abstract available.
1,2,4-Triazolyl 5-Azaspiro[2.4]heptanes: Lead Identification and Early Lead Optimization of a New Series of Potent and Selective Dopamine D3 Receptor Antagonists.
Micheli F, Bacchi A, Braggio S, Castelletti L, Cavallini P, Cavanni P, Cremonesi S, Dal Cin M, Feriani A, Gehanne S, Kajbaf M, Marchió L, Nola S, Oliosi B, Pellacani A, Perdonà E, Sava A, Semeraro T, Tarsi L, Tomelleri S, Wong A, Visentini F, Zonzini L, Heidbreder C. Micheli F, et al. Among authors: perdona e. J Med Chem. 2016 Sep 22;59(18):8549-76. doi: 10.1021/acs.jmedchem.6b00972. Epub 2016 Sep 9. J Med Chem. 2016. PMID: 27564135
15 results