Mertz TM - Search Results

1

A cancer-associated DNA polymerase delta variant modeled in yeast causes a catastrophic increase in genomic instability.

Daee DL, Mertz TM, Shcherbakova PV. Daee DL, et al. Among authors: mertz tm. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):157-62. doi: 10.1073/pnas.0907526106. Epub 2009 Dec 4. Proc Natl Acad Sci U S A. 2010. PMID: 19966286 Free PMC article.

2

Nucleotide selectivity defect and mutator phenotype conferred by a colon cancer-associated DNA polymerase δ mutation in human cells.

Mertz TM, Baranovskiy AG, Wang J, Tahirov TH, Shcherbakova PV. Mertz TM, et al. Oncogene. 2017 Aug;36(31):4427-4433. doi: 10.1038/onc.2017.22. Epub 2017 Apr 3. Oncogene. 2017. PMID: 28368425 Free PMC article.

3

DNA polymerases ζ and Rev1 mediate error-prone bypass of non-B DNA structures.

Northam MR, Moore EA, Mertz TM, Binz SK, Stith CM, Stepchenkova EI, Wendt KL, Burgers PM, Shcherbakova PV. Northam MR, et al. Among authors: mertz tm. Nucleic Acids Res. 2014 Jan;42(1):290-306. doi: 10.1093/nar/gkt830. Epub 2013 Sep 18. Nucleic Acids Res. 2014. PMID: 24049079 Free PMC article.

4

DNA polymerase ζ-dependent lesion bypass in Saccharomyces cerevisiae is accompanied by error-prone copying of long stretches of adjacent DNA.

Kochenova OV, Daee DL, Mertz TM, Shcherbakova PV. Kochenova OV, et al. Among authors: mertz tm. PLoS Genet. 2015 Mar 31;11(3):e1005110. doi: 10.1371/journal.pgen.1005110. eCollection 2015 Mar. PLoS Genet. 2015. PMID: 25826305 Free PMC article.

5

Colon cancer-associated mutator DNA polymerase δ variant causes expansion of dNTP pools increasing its own infidelity.

Mertz TM, Sharma S, Chabes A, Shcherbakova PV. Mertz TM, et al. Proc Natl Acad Sci U S A. 2015 May 12;112(19):E2467-76. doi: 10.1073/pnas.1422934112. Epub 2015 Mar 31. Proc Natl Acad Sci U S A. 2015. PMID: 25827231 Free PMC article.

6

Postreplication repair inhibits CAG.CTG repeat expansions in Saccharomyces cerevisiae.

Daee DL, Mertz T, Lahue RS. Daee DL, et al. Mol Cell Biol. 2007 Jan;27(1):102-10. doi: 10.1128/MCB.01167-06. Epub 2006 Oct 23. Mol Cell Biol. 2007. PMID: 17060452 Free PMC article.

7

A reversible histone H3 acetylation cooperates with mismatch repair and replicative polymerases in maintaining genome stability.

Kadyrova LY, Mertz TM, Zhang Y, Northam MR, Sheng Z, Lobachev KS, Shcherbakova PV, Kadyrov FA. Kadyrova LY, et al. Among authors: mertz tm. PLoS Genet. 2013 Oct;9(10):e1003899. doi: 10.1371/journal.pgen.1003899. Epub 2013 Oct 24. PLoS Genet. 2013. PMID: 24204308 Free PMC article.

8

Histone deacetylase complexes promote trinucleotide repeat expansions.

Debacker K, Frizzell A, Gleeson O, Kirkham-McCarthy L, Mertz T, Lahue RS. Debacker K, et al. PLoS Biol. 2012 Feb;10(2):e1001257. doi: 10.1371/journal.pbio.1001257. Epub 2012 Feb 21. PLoS Biol. 2012. PMID: 22363205 Free PMC article.

9

APOBEC3A is a prominent cytidine deaminase in breast cancer.

Cortez LM, Brown AL, Dennis MA, Collins CD, Brown AJ, Mitchell D, Mertz TM, Roberts SA. Cortez LM, et al. Among authors: mertz tm. PLoS Genet. 2019 Dec 16;15(12):e1008545. doi: 10.1371/journal.pgen.1008545. eCollection 2019 Dec. PLoS Genet. 2019. PMID: 31841499 Free PMC article.

10

The Shu complex prevents mutagenesis and cytotoxicity of single-strand specific alkylation lesions.

Bonilla B, Brown AJ, Hengel SR, Rapchak KS, Mitchell D, Pressimone CA, Fagunloye AA, Luong TT, Russell RA, Vyas RK, Mertz TM, Zaher HS, Mosammaparast N, Malc EP, Mieczkowski PA, Roberts SA, Bernstein KA. Bonilla B, et al. Among authors: mertz tm. Elife. 2021 Nov 1;10:e68080. doi: 10.7554/eLife.68080. Elife. 2021. PMID: 34723799 Free PMC article.

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