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Paradoxical effects of increased expression of PGC-1alpha on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism.
Choi CS, Befroy DE, Codella R, Kim S, Reznick RM, Hwang YJ, Liu ZX, Lee HY, Distefano A, Samuel VT, Zhang D, Cline GW, Handschin C, Lin J, Petersen KF, Spiegelman BM, Shulman GI. Choi CS, et al. Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19926-31. doi: 10.1073/pnas.0810339105. Epub 2008 Dec 9. Proc Natl Acad Sci U S A. 2008. PMID: 19066218 Free PMC article.
Loss of the Par-1b/MARK2 polarity kinase leads to increased metabolic rate, decreased adiposity, and insulin hypersensitivity in vivo.
Hurov JB, Huang M, White LS, Lennerz J, Choi CS, Cho YR, Kim HJ, Prior JL, Piwnica-Worms D, Cantley LC, Kim JK, Shulman GI, Piwnica-Worms H. Hurov JB, et al. Among authors: choi cs. Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5680-5. doi: 10.1073/pnas.0701179104. Epub 2007 Mar 19. Proc Natl Acad Sci U S A. 2007. PMID: 17372192 Free PMC article.
Urocortin 2 modulates glucose utilization and insulin sensitivity in skeletal muscle.
Chen A, Brar B, Choi CS, Rousso D, Vaughan J, Kuperman Y, Kim SN, Donaldson C, Smith SM, Jamieson P, Li C, Nagy TR, Shulman GI, Lee KF, Vale W. Chen A, et al. Among authors: choi cs. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16580-5. doi: 10.1073/pnas.0607337103. Epub 2006 Oct 18. Proc Natl Acad Sci U S A. 2006. PMID: 17050686 Free PMC article.
Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity.
Choi CS, Savage DB, Abu-Elheiga L, Liu ZX, Kim S, Kulkarni A, Distefano A, Hwang YJ, Reznick RM, Codella R, Zhang D, Cline GW, Wakil SJ, Shulman GI. Choi CS, et al. Proc Natl Acad Sci U S A. 2007 Oct 16;104(42):16480-5. doi: 10.1073/pnas.0706794104. Epub 2007 Oct 8. Proc Natl Acad Sci U S A. 2007. PMID: 17923673 Free PMC article.
455 results